1722-11-8

1722-11-8 - Names and Identifiers

Name	1-(6-Chloro-pyridazino-3-yl)piperidine
Synonyms	3-Chloro-6-piperidinopyridazine 3-chloro-6-(1-piperidyl)pyridazine 3-Chloro-6-piperidin-1-yl-pyridazine 3-CHLORO-6-PIPERIDIN-1-YL-PYRIDAZINE 3-CHLORO-6-(1-PIPERIDINYL)PYRIDAZINE 1-(6-CHLORO-PYRIDAZINO-3-YL)PIPERIDINE 1-(6-Chloro-pyridazino-3-yl)piperidine Pyridazine, 3-chloro-6-(1-piperidinyl)- 3-chloro-6-piperidin-1-ylpyridazine hydrochloride
CAS	1722-11-8
EINECS	200-001-2
InChI	InChI=1/C9H12ClN3/c10-8-4-5-9(12-11-8)13-6-2-1-3-7-13/h4-5H,1-3,6-7H2

1722-11-8 - Physico-chemical Properties

Molecular Formula	C9H12ClN3
Molar Mass	197.66
Density	1.234±0.06 g/cm3(Predicted)
Melting Point	80～82℃
Boling Point	388.6±27.0 °C(Predicted)
Flash Point	188.8°C
Vapor Presure	3.02E-06mmHg at 25°C
pKa	3.62±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.564

1722-11-8 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

1722-11-8 - Introduction

1-(6-choro-pyriridazino-3-yl) piperidine is an organic compound with the chemical formula C11H12ClN3. It is a white solid, crystal form at room temperature. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(6-chroo-pyridazino-3-yl) piperidine is a compound with a neutral character. It has good stability and low solubility and can exist as a solid at room temperature. It has a melting point of about 140-142°C and a boiling point of about 319°C.

Use:
1-(6-chroo-pyridazino-3-yl) piperidine has certain application value in the field of pharmacy, and is often used as a synthetic intermediate of anti-cancer drugs. It can be used to synthesize a variety of anticancer drugs, including some inhibitors of targeted kinases.

Method:
The preparation method of 1-(6-chroo-pyridazino-3-yl) piperidine is relatively complicated, and generally requires a multi-step reaction to synthesize. Among them, the common preparation method includes reacting 6-chloropyridazine with aminopiperidine, and carrying out reaction and separation and purification under appropriate conditions, and finally obtaining the target product.

Safety Information:
1-(6-chroo-pyridazino-3-yl) piperidine has no obvious harmful effect on human body and environment under normal use conditions. However, as a chemical substance, care should be taken to comply with relevant safe operating procedures when handling and using. It may irritate the eyes, skin and respiratory system, so avoid direct contact with it and operate in a well-ventilated place.

Last Update：2024-04-09 20:45:29