172299-81-9

172299-81-9 - Names and Identifiers

Name	N-Boc-N-methoxy-3-aminopropionic acid
Synonyms	N-Boc-N-methoxy-3-aminopropionic acid 3-(Tert-butoxycarbonyl(methoxy)amino)propanoic acid b-Alanine,N-[(1,1-diMethylethoxy)carbonyl]-N-Methoxy- β-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-N-methoxy- N-[(1,1-Dimethylethoxy)carbonyl]-N-methoxy-beta-alanine 3-[METHOXY-[(2-METHYLPROPAN-2-YL)OXYCARBONYL]AMINO]PROPANOIC ACID
CAS	172299-81-9

172299-81-9 - Physico-chemical Properties

Molecular Formula	C9H17NO5
Molar Mass	219.24
Density	1.160±0.06 g/cm3(Predicted)
Boling Point	327.8±25.0 °C(Predicted)
pKa	4.46±0.10(Predicted)
Storage Condition	2-8°C

172299-81-9 - Introduction

N-Boc-N-methoxy-3-aminopropionic acid is an organic compound whose chemical name is N-tert-butoxycarbonyl-N-methoxy-3-amino propanoic acid. The following is a detailed description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C9H17NO4
-Molecular weight: 203.24g/mol
-Melting point: 150-155 ° C
-Solubility: Soluble in ether, chloroform and dichloromethane, slightly soluble in ethanol

Use:
N-Boc-N-methoxy-3-aminopropionic acid is commonly used as a starting material for the synthesis of drugs and ligands and has the following main uses:
-For the synthesis of biologically active peptides and protein compounds, widely used in the field of drug research and development.
-As an auxiliary ligand for Some catalysts, it is used in organic synthesis reactions and catalytic reactions.

Method:
The preparation of N-Boc-N-methoxy-3-aminopropionic acid is usually carried out by the following steps:
1. First, n-methoxy-3-aminopropionic acid is reacted with Tetra-tert-butyl carbonate (t-BOC-Cl) in the presence of a base to obtain N-Boc-N-methoxy-3-aminopropionic acid tetra-tert-butyl ester.
2. Hydrolyze the reaction product and alkali to generate N-Boc-N-methoxy-3-aminopropionic acid.

Safety Information:
N-Boc-N-methoxy-3-aminopropionic acid is generally safe under normal use conditions, but the following matters still need to be paid attention:
-May be irritating and corrosive to the skin, eyes and respiratory system. Wear protective gloves, goggles and a mask when used.
-Avoid inhalation, ingestion, or contact with skin. Use with good laboratory practice.
-During storage and transportation, avoid contact with oxidants, strong acids, strong bases and other substances to avoid dangerous situations.

In addition, before using N-Boc-N-methoxy-3-aminopropionic acid, it is recommended to review the relevant literature and ensure that proper laboratory safety practices are followed.

Last Update：2024-04-09 15:17:53