172361-60-3

172361-60-3 - Names and Identifiers

Name	5'-O-(Dimethoxytrityl)-N2-(Dimethylaminomethylidene)-3'-Deoxyguanosine
Synonyms	DMT-DMF-dG 5'-DMT-DMF-dG 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-Deoxy-N2-DMF-5'-O-tritylguanosine 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE 5'-O-(Dimethoxytrityl)-N2-(Dimethylaminomethylidene)-3'-Deoxyguanosine 2'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-N-[(dimethylamino)methylene]guanosine Guanosine, 2'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-N-[(dimethylamino)methylene]- (9CI)
CAS	172361-60-3
EINECS	2017-001-1

172361-60-3 - Physico-chemical Properties

Molecular Formula	C34H36N6O6
Molar Mass	624.69
Density	1.32±0.1 g/cm3(Predicted)
pKa	9.55±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature

172361-60-3 - Introduction

5 '-O-(Dimethoxytrityl)-N2-(dimethylaminomethyl lidene)-3'-Deoxyguanosine is an organic compound also known as n2-dimethylformamide-2 '-deoxydeoxyguanosine. It is a nucleoside compound that consists of a dimethylformamidine group and a 2 '-deoxyguanosine group in its chemical structure. Its chemical formula is C12H17N5O4 and its molecular weight is 303.29g/mol.

5 '-O-(Dimethoxytrityl)-N2-(dimethylaminomethyl lidene)-3'-Deoxyguanosine has antiviral activity, especially for Herpes Simplex Virus (HSV) and other viruses. It is used as a reagent in antiviral drug research. In addition, 5 '-O-(Dimethoxytrityl)-N2-(dimethylaminomethyl lidene)-3'-Deoxyguanosine can also be used as an intermediate in the synthesis of nucleoside drugs.

The method for preparing 5 '-O-(Dimethoxytrityl)-N2-(dimethylaminometlylidene)-3'-Deoxyguanosine is generally by organic chemical synthesis. In particular, the desired product can be obtained by reacting 2 '-deoxyguanosine with dimethylformamidine.

Regarding safety information, there is no sufficient research data on the toxicity and danger of 5 '-O-(Dimethoxytrityl)-N2-(dimethylaminometlylidene)-3'-Deoxyguanosine. However, as a chemical substance, it should strictly follow safe operating procedures and ensure that it is used under suitable laboratory conditions. Care should be taken to prevent contact with skin, eyes and ingestion, and to avoid inhalation of dust or vapors. If exposed or inhaled, seek medical help immediately. During use and storage, it should be kept away from ignition and oxidizing agents and properly sealed.

Last Update：2024-04-09 20:15:17