172875-53-5

172875-53-5 - Names and Identifiers

Name	Olmesartan intermediate impurity I
Synonyms	Ethyl 4-(2-hydroxybutan-2-yl) Olmesartan intermediate impurity Ⅲ OlMesartan interMediate iMpurity I Olmesartan intermediate impurity I OlMesartan interMediate iMpurity V -2-propyl-1H-imidazole-5-carboxylate ethyl 4-(2-hydroxybutan-2-yl)-2-propyl-1H-imidazole-5-carboxylate Ethyl 4-(2-hydroxybutan-2-yl)-2-propyl-1H-imidazole-5-carboxylate 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1H-Imidazole-5-carboxylic acidethylester 4-(1-hydroxy-1-methylpropyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester 1H-iMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylpropyl)-2-propyl-, ethyl ester
CAS	172875-53-5

172875-53-5 - Physico-chemical Properties

Molecular Formula	C13H22N2O3
Molar Mass	254.33
Density	1.111±0.06 g/cm3(Predicted)
Boling Point	464.9±35.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Gel
Color	Colourless
pKa	12.97±0.10(Predicted)
Storage Condition	2-8°C
Use	Intermediate

172875-53-5 - Introduction

imidazole monoethyl ester (Methyl imidazole) is a common impurity and is referred to as imidazolone for short. The following is a description of its nature, use, preparation and safety information:

Nature:
Olmesartan intermediate impurity I is a colorless liquid with a special odor. Its molecular formula is C4H6N2O and its molecular weight is 98.10g/mol. This impurity has moderate volatility and solubility and is soluble in water and organic solvents.

Use:
Olmesartan intermediate impurity I is a commonly used organic synthesis intermediate. It is commonly used in the fields of drug synthesis, dye synthesis and chemical synthesis. In organic synthesis, it is often used as a catalyst, reaction intermediary or hydroxide scavenger.

Method:
Olmesartan intermediate impurity I can be obtained by reacting imidazole with ethanol under appropriate conditions. This reaction is generally carried out at a higher temperature, the common method is heating under alkaline conditions, and the catalyst is often basic zinc oxide or basic zinc carbonate.

Safety Information:
The Olmesartan intermediate impurity I is generally less toxic. However, long-term exposure may cause irritation to the skin, eyes and respiratory tract. Therefore, when handling Olmesartan intermediate impurity I, correct laboratory safety procedures should be followed to avoid direct skin contact and inhalation. The Material Safety Data Sheet should be read carefully before use and relevant safety precautions should be followed.

Last Update：2024-04-09 20:48:19