17288-45-8

17288-45-8 - Names and Identifiers

Name	(5-methoxy-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol
Synonyms	5-Methoxy-4-azaindole-2-methanol (6-Methoxy-7-azaindole-2-yl)methanol 5-methoxy-1H-Pyrrolo[3,2-b]pyridine-2-methanol 1H-pyrrolo[3,2-b]pyridine-2-methanol, 5-methoxy- 1H-Pyrrolo[3,2-b]pyridine-2-methanol, 5-methoxy- (5-Methoxy-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol (5-METHOXY-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)METHANOL (5-methoxy-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol
CAS	17288-45-8
InChI	InChI=1/C9H10N2O2/c1-13-9-3-2-7-8(11-9)4-6(5-12)10-7/h2-4,10,12H,5H2,1H3

17288-45-8 - Physico-chemical Properties

Molecular Formula	C9H10N2O2
Molar Mass	178.19
Density	1.34g/cm³
Boling Point	383.4°C at 760 mmHg
Flash Point	185.7°C
Vapor Presure	1.46E-06mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.671

17288-45-8 - Risk and Safety

HS Code

29349990

17288-45-8 - Introduction

(5-methoxy-1hrrolo [3,2-b]pyridin-2-yl)methanol, also known as (methanol) methanol, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance:(5-methoxy-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol is a light yellow to yellow crystalline powder.
-Melting point: Its melting point is usually between 160-162°C.
-Solubility: It can be dissolved in some organic solvents, such as methanol, ethanol and dichloromethane.

Use:
(5-methoxy-1h-prrolo [3,2-b]pyridin-2-yl)methanol is usually used in organic synthesis as an intermediate or an important raw material for drug synthesis.

Method:
This compound can be synthesized by the following steps:
1.2-nitroindole is reacted with formaldehyde under alkaline conditions to obtain (6-methoxy -7-nitroindol-2-yl) methanol.
2. (6-methoxy-7-nitroindol-2-yl) methanol was treated under denitration conditions to obtain the target product (5-methoxy-1h-pyridrolo [3,2-b]pyridin-2-yl)methanol.

Safety Information:
- (5-methoxy-1h-yrrolo [3,2-b]pyridin-2-yl)methanol should be stored in a dry, well-ventilated place away from open flames and high temperatures.
-Appropriate personal protective equipment, such as respirators, gloves and eye protection, must be worn during use and operation.
-Due to the lack of sufficient toxicity data, there is currently no information on the main toxicity and hazards of this compound. Use with caution and follow proper laboratory practices. Without understanding its toxicity and danger, it is best to treat it as a hazardous substance.

Last Update：2024-04-09 21:32:38