1737-06-0

1737-06-0 - Names and Identifiers

Name	4-(trifluoromethoxy)acetanilide
Synonyms	4-(TRIFLUOROMETHOXY)ACETANILIDE 4-(trifluoromethoxy)acetanilide 4'-(TRIFLUOROMETHOXY)ACETANILIDE N-[4-(trifluoromethoxy)phenyl]acetamide N-(4-(trifluoroMethoxy)phenyl)acetaMide N1-[4-(TRIFLUOROMETHOXY)PHENYL]ACETAMIDE Acetamide, N-[4-(trifluoromethoxy)phenyl]- alpha,alpha,alpha-Trifluoro-p-acetanisidide p-Acetanisidide, alpha,alpha,alpha-trifluoro-
CAS	1737-06-0
InChI	InChI=1/C9H8F3NO2/c1-6(14)13-7-2-4-8(5-3-7)15-9(10,11)12/h2-5H,1H3,(H,13,14)

1737-06-0 - Physico-chemical Properties

Molecular Formula	C9H8F3NO2
Molar Mass	219.16
Density	1.345±0.06 g/cm3(Predicted)
Melting Point	115-117°C
Boling Point	296.8±40.0 °C(Predicted)
Flash Point	133.3°C
Vapor Presure	0.00141mmHg at 25°C
pKa	14.14±0.70(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.496

1737-06-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
Hazard Class	IRRITANT

1737-06-0 - Introduction

4-(trifluoromethoxy)acetanilide is an organic compound with the chemical formula C9H9F3NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-(trifluoromethoxy)acetanilide is a white crystal or crystalline powder.
-Solubility: It is soluble in organic solvents such as ethanol, chloroform and dichloromethane. Its solubility in water is relatively low.
-Stability: The compound is stable and not easy to decompose under regular storage conditions.

Use:
- 4-(trifluoromethoxy)acetanilide is mainly used for protecting group reactions in organic synthesis. It can be used as an introduction agent for a protecting group (commonly referred to as a "protecting Group"), which is used to protect certain functional groups in the compound during the reaction to avoid accidental chemical reactions.
-In addition, it can also be used to synthesize other organic compounds, such as drugs, dyes and pesticides.

Method:
The preparation method of -4-(trifluoromethoxy)acetanilide can be obtained by reacting 4-aminoacetanilide with methyl trifluoroformate. The reaction conditions generally require the use of base catalysis.

Safety Information:
-Since 4-(trifluoromethoxy)acetanilide is an organic compound, it should be treated with caution and avoid contact with skin and eyes.
-Good laboratory safety practices such as wearing protective gloves, goggles, and laboratory coats should be followed when using the compound.
-When using or handling this compound, maintain a well-ventilated working environment and avoid inhaling its gas or dust.
-According to the characteristics of chemicals, they should be stored properly, avoid contact with flammable substances, and keep away from open flames and high temperatures.
-During handling, care should be taken to avoid leakage and spillage of chemicals.

Last Update：2024-04-09 21:04:16