17391-18-3
Corynoxine B
CAS: 17391-18-3
Molecular Formula: C22H28N2O4
17391-18-3 - Names and Identifiers
| Name | Corynoxine B |
| Synonyms | Corynoxine B 7-Isocorynoxine (7R,16E)-17-Methoxy-2-oxo-20betaH-corynox-16-en-16-carbonsae Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'R,6'S,7'S,8'aS)- |
| CAS | 17391-18-3 |
17391-18-3 - Physico-chemical Properties
| Molecular Formula | C22H28N2O4 |
| Molar Mass | 384.48 |
| Density | 1.23±0.1 g/cm3(Predicted) |
| Boling Point | 560.8±50.0 °C(Predicted) |
| Solubility | DMSO : 83.33 mg/mL (216.74 mM; Need ultrasonic) |
| Appearance | Powder |
| pKa | 13.61±0.60(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD22124999 |
| Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Rubiaceae plant Uncaria. |
17391-18-3 - Reference
| Reference Show more | 1. [IF=4.411] Shugen Wei et al."Molecular Identification and Targeted Quantitative Analysis of Medicinal Materials from Uncaria Species by DNA Barcoding and LC-MS/MS."Molecules. 2019 Jan;24(1):175 2. [IF=3.935] Shuanglu Xie et al."Systematic identification and quantification of tetracyclic monoterpenoid oxindole alkaloids in Uncaria rhynchophylla and their fragmentations in Q-TOF-MS spectra."J Pharmaceut Biomed. 2013 Jul;81-82:56 3. [IF=4.759] Keyu Feng et al."Configuration of the ion exchange chromatography, hydrophilic interaction chromatography, and reversed-phase chromatography as off-line three-dimensional chromatography coupled with high-resolution quadrupole-Orbitrap mass spectrometry fo |
17391-18-3 - Reference Information
| biological activity | konosin B(Corynoxine B) is a natural compound of indole alkaloids, a beclin-1-dependent autophagy inducer. |
| chemical properties | white powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Rubiaceae plant Uncaria. |
| use | konosin B has the effects of lowering blood pressure, resisting arrhythmia and protecting cerebral hypoxia and ischemia. used for content determination/identification/pharmacological experiment, etc. |
Last Update：2024-04-09 21:01:54
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Mobile: 18021002903
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