Name | 1-Butyl-3-methylimidazolium tetrafluoroborate |
Synonyms | 1-Butyl-3-methylimidazolium terafluoroborate 1-Butyl-3-methylimidazolium tetrafluoroborate 1-N-BUTYL-3-METHYLIMIDAZOLIUM TETRAFLUOROBORATE 1-n-Butyl-3-methylimidazolium tetrafluoroborate 1-butyl-3-methyl-1H-imidazol-3-ium tetrafluoroborate 1-Butyl-3-methylimidazolium tetrafluoroborate,BMIMBF4 1-Butyl-3-methylimidazolium tetrafluoroborate,BMIMBF4, Basionics EE 04 |
CAS | 174501-65-6 |
EINECS | 638-831-1 |
InChI | InChI=1/C8H15N2.BF4/c1-3-4-5-10-7-6-9(2)8-10;2-1(3,4)5/h6-8H,3-5H2,1-2H3;/q+1;-1 |
InChIKey | YKVHBSVCYVBXQM-UHFFFAOYSA-M |
Molecular Formula | C8H15BF4N2 |
Molar Mass | 226.02 |
Density | 1.21 g/mL at 20 °C (lit.) |
Melting Point | -71 °C |
Flash Point | 288°C |
Water Solubility | Miscible with acetone, acetonitrile, ethyl acetate, isopropyl alcohol and methylene chloride. Immiscible with hexane, toluene and water. |
Appearance | Clear liquid |
Color | Clear yellow-orange |
PH | 5 (H2O, 20℃) |
Storage Condition | Store below +30°C. |
Stability | hygroscopic |
Sensitive | Easily absorbing moisture |
Refractive Index | n20/D 1.52 |
MDL | MFCD03095449 |
Physical and Chemical Properties | Density 1.2077 melting point -71°C refractive index 1.52 |
Use | Ionic liquids can be used in many reactions, such as hydrogenation reactions; asymmetric hydrogenation reactions have higher enantioselectivity than homogeneous hydrogenation reactions; and Suzuki cross-coupling reactions at room temperature. |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/38 - Irritating to eyes and skin. R25 - Toxic if swallowed |
Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN2810 6.1/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 2933 29 90 |
Hazard Class | 9 |
Packing Group | Ⅲ |
Reference Show more | 1. Zhang Yuanyuan, Hu Yanzhen, Tian Yingying, et al. Separation of indole alkaloids by high performance liquid chromatography with ionic liquid as mobile phase additive [J]. Journal of Pharmaceutical Analysis, 2019, 039(011):2028-2033. 2. Liu, Yuanyuan, et al. "Isolation and purification of alkaloids from the Macleaya cordata by ionic ‐liquid-modified high‐speed counter-current chromatography." Journal of separation science 43.12 (2020): 2459-2466.https://doi.org/10.1002/jssc.20190 3. Wu, Nan, et al. "Isolation and purification of alkaloids from lotus leaves by ionic‐liquid-modified high‐speed countercurrent chromatography." Journal of separation science 41.2 (2018): 571-577.https:// doi.org/10.1002/jssc.201700851 4. [IF = 3.645] Nan Wu et al. "Isolation and purification of alkaloids from lotus leaves by ionic-liquid-modified high-speed countercurrent chromatography." J SepSci. 2018 Jan;41(2): 571-577 5. [IF = 3.645] Yuanyuan Liu et al. "Isolation and purification of alkaloids from the fruit of Macleaya cordata by ionic-liquid-modified high-speed counter-current chromatography." J Sep Sci. 2020 Jun;43(12): 2459-2466 6. [IF = 2.044] Liu Cong et al. "Isolation of Four Major Compounds of γ-Oryzanol from Rice Bran Oil by Ionic Liquids Modified High-Speed Countercurrent Chromatography and Antimicrobial Activity and Neuroprotective Effect of Cycloartenyl Ferulate In Vitro." Chromatographia |
Application | 1-butyl-3-methylimidazolium tetrafluoroborate as the bulk solvent phase, which is a recyclable alternative to conventional organic solvents Provides new opportunities for biocatalytic production of commercially important chemicals, including asymmetric synthesis, and in some cases improves product formation rate and enantioselectivity. 1-Butyl-3-methylimidazolium tetrafluoroborate has been used as an enzyme coating for the development of recyclable heterogeneous biocatalysts, as an immobilized carrier for enzymes in biphasic systems in continuous phase systems employing ScCO2, and as a component of a supporting liquid membrane for the continuous separation of reactants and products in enzyme-catalyzed reactions. |
Uses | Ionic liquids can be used in many reactions, such as hydrogenation reactions; asymmetric hydrogenation reactions are more enantioselective than homogeneous hydrogenation reactions; and Used for Suzuki cross-coupling reactions at room temperature. Ionic liquids can be used in many reactions, such as hydrogenation or asymmetric hydrogenation, compared with the homogeneous phase, it has higher enantioselectivity; Suzuki cross-coupling reaction at room temperature |