174885-99-5

174885-99-5 - Names and Identifiers

Name	tert-butyl (2-amino-2-phenylethyl)carbamate
Synonyms	tert-butyl (2-amino-2-phenylethyl)carbamate tert-Butyl (2-aMino-2-phenylethyl)carbaMate tert-butyl N-(2-amino-2-phenylethyl)carbamate 2-Methyl-2-propanyl-(2-amino-2-phenylethyl)carbamat 2-Methyl-2-propanyl (2-amino-2-phenylethyl)carbamate (2-Amino-2-phenylethyl)carbamic acid tert-butyl ester (2-AMINO-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER (2-Amino-2-Phenyl-Ethyl)-Carbamic Acid Tert-Butyl Ester carbamic acid, N-(2-amino-2-phenylethyl)-, 1,1-dimethylethyl ester Carbamic acid, N-(2-amino-2-phenylethyl)-, 1,1-dimethylethyl ester
CAS	174885-99-5
InChI	InChI=1/C13H20N2O2/c1-13(2,3)17-12(16)15-9-11(14)10-7-5-4-6-8-10/h4-8,11H,9,14H2,1-3H3,(H,15,16)

174885-99-5 - Physico-chemical Properties

Molecular Formula	C13H20N2O2
Molar Mass	236.31
Density	1.066±0.06 g/cm3(Predicted)
Boling Point	375.2±35.0 °C(Predicted)
Flash Point	180.7°C
Vapor Presure	7.89E-06mmHg at 25°C
pKa	12.29±0.46(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.524

174885-99-5 - Introduction

tert-butyl (2-amino-2-phenylethyl)carbamate, also known as Boc-glycine tert-butyl ester, is a commonly used organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless or light yellow liquid, which may become solid over time.
-molecular formula: C13H21NO4
-Molecular Weight: 255.31
-Melting Point: 78-80 ℃
-Boiling Point: 206-207 ℃(1.5 mmHg)
-Solubility: Soluble in alcohol, ether, ketone and Ester, slightly soluble in water.

Use:
- Boc-glycine tert-butyl ester is a commonly used protecting group compound, which is widely used in chemical synthesis.
-It can be used as an intermediate for the synthesis of polypeptides and pharmaceutical compounds.
-Because of its stability and easy removal of protecting groups, it is used to protect amino acids and peptide chains.

Method:
The preparation method of Boc-glycine tert-butyl ester is as follows:
1. (2-amino-2-phenylethyl)-carbamic acid is reacted with tert-butanol to produce a tert-butyl ester compound.
2. Under the action of a base, the formed tert-butyl ester compound is subjected to a protecting reaction to obtain tert-butyl Boc-glycine.

Safety Information:
- Boc-glycine tert-butyl ester is an organic compound and should comply with regular laboratory safety procedures.
-in the use and storage process, should avoid direct contact with the skin and eyes; Such as accidental contact, the application of plenty of water rinse.
-Avoid inhalation or ingestion during operation.
-Should be stored in a cool, dry, well-ventilated place, and stored separately from the oxidant.

Please note that the above information is for professional and laboratory use only. Non-professionals are advised to avoid contact and handling of the compounds. Always consult accurate chemical safety information and operating manuals before use.

Last Update：2024-04-09 21:04:16