175205-77-3
4-chloro-2-(trifluoromethoxy)aniline
CAS: 175205-77-3
Molecular Formula: C7H5ClF3NO
175205-77-3 - Names and Identifiers
175205-77-3 - Physico-chemical Properties
| Molecular Formula | C7H5ClF3NO |
| Molar Mass | 211.57 |
| Density | 1.468±0.06 g/cm3(Predicted) |
| Melting Point | 31-33℃ |
| Boling Point | 82 °C |
| Flash Point | 72.3°C |
| Water Solubility | Sparingly soluble in water 0.25 g/L @25°C. |
| Vapor Presure | 0.573mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | White |
| pKa | 1.81±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.471 |
| MDL | MFCD00153102 |
175205-77-3 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 3276 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
175205-77-3 - Introduction
4-chloro-2-(trifluoromethoxy)aniline is an organic compound with the chemical formula C7H5ClF3NO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 4-chloro-2-(trifluoromethoxy)aniline is a white crystalline solid.
-Melting point: About 60-62 degrees Celsius.
-Boiling point: About 212 degrees Celsius.
-Solubility: Soluble in water, soluble in organic solvents such as alcohol and ether.
Use:
- 4-chloro-2-(trifluoromethoxy)aniline can be used as an intermediate in organic synthesis and can be used to prepare other organic compounds.
-Due to its unique structure and properties, it can also be used for drug research and development in the pharmaceutical field.
Method:
- 4-chloro-2-(trifluoromethoxy)aniline is usually obtained by amination reaction. First, 4-chloro-2-(trifluoromethoxy) benzeneboronic acid is reacted with ammonia to form 4-chloro-2-(trifluoromethoxy)aniline.
Safety Information:
- 4-chloro-2-(trifluoromethoxy)aniline is an organic compound, so you should pay attention to safety when using and storing it.
-Prolonged contact with skin should be avoided, especially to avoid entering the eyes or inhaling into the respiratory system.
-Wear protective glasses, gloves and breathing apparatus during use.
-If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical help.
Please note that the above information is for reference only. Please follow the corresponding safety procedures when using or handling chemicals, and follow laboratory safety and personal protective measures.
Nature:
-Appearance: 4-chloro-2-(trifluoromethoxy)aniline is a white crystalline solid.
-Melting point: About 60-62 degrees Celsius.
-Boiling point: About 212 degrees Celsius.
-Solubility: Soluble in water, soluble in organic solvents such as alcohol and ether.
Use:
- 4-chloro-2-(trifluoromethoxy)aniline can be used as an intermediate in organic synthesis and can be used to prepare other organic compounds.
-Due to its unique structure and properties, it can also be used for drug research and development in the pharmaceutical field.
Method:
- 4-chloro-2-(trifluoromethoxy)aniline is usually obtained by amination reaction. First, 4-chloro-2-(trifluoromethoxy) benzeneboronic acid is reacted with ammonia to form 4-chloro-2-(trifluoromethoxy)aniline.
Safety Information:
- 4-chloro-2-(trifluoromethoxy)aniline is an organic compound, so you should pay attention to safety when using and storing it.
-Prolonged contact with skin should be avoided, especially to avoid entering the eyes or inhaling into the respiratory system.
-Wear protective glasses, gloves and breathing apparatus during use.
-If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical help.
Please note that the above information is for reference only. Please follow the corresponding safety procedures when using or handling chemicals, and follow laboratory safety and personal protective measures.
Last Update：2024-04-09 21:01:54
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View History
175205-77-3
7790-59-2
515-30-0
5736-91-4
2973-78-6
1,4-Diethylenedioxide
1H-Pyrrolizine-1-carboxaldehyde, hexahydro-3-oxo-, (1R-cis)- (9CI)
68837-61-6
2105-61-5
3-(Methylsulfonyl)propan-1-ol
7790-59-2
515-30-0
5736-91-4
2973-78-6
1,4-Diethylenedioxide
1H-Pyrrolizine-1-carboxaldehyde, hexahydro-3-oxo-, (1R-cis)- (9CI)
68837-61-6
2105-61-5
3-(Methylsulfonyl)propan-1-ol