175357-18-3
UNDECYLENOYL PHENYLALANINE
CAS: 175357-18-3
Molecular Formula: C20H29NO3
175357-18-3 - Names and Identifiers
175357-18-3 - Physico-chemical Properties
| Molecular Formula | C20H29NO3 |
| Molar Mass | 331.45 |
| Density | 1.047±0.06 g/cm3(Predicted) |
| Melting Point | 109-112 °C |
| Boling Point | 540.0±50.0 °C(Predicted) |
| Storage Condition | 2-8℃ |
| Use | Use undecylenyl phenylalanine (MoreWhiteUP) is a white powder. It is a structural analog of α-MSH, and by competitively binding to melanocyte stimulating hormone receptor MC1-R on melanocytes, melanocytes cannot produce tyrosinase, thereby inhibiting melanocyte activity and reducing melanin production. According to some clinical trials, it has been shown that undecenoyl phenylalanine (morewhiteu chemical bookp) can indeed reduce the formation of spots due to pigmentation. Undecenoyl phenylalanine has a good skin-friendly, can control alpha-MSH (melanocyte stimulating hormone) and melanin production factor binding, thereby blocking the process of melanin formation. Blocking α-MSH can be performed at a concentration of 0.001%, while the optimal use concentration is 1%. From multiple links to inhibit melanin production, the effect is more obvious, lasting. |
175357-18-3 - Synthesis of undecylenyl phenylalanine and its inhibition on tyrosinase diphenolase activity
from VIP
Author:
Abstract:
sodium undecenoyl phenylalanine was synthesized by condensation reaction of 11 enoic acid and phenylalanine, using sulfoxide chloride to chloride the 11 enoic acid, and by means of the Xiao-Bowman method (Schotten-Baumann), undecylenyl phenylalanine was obtained after separation by acidification. The structure of the synthesized product was characterized by IR,MS and ~ 1H NMR, and the inhibitory mechanism of undecylenyl phenylalanine on tyrosinase diphenolase activity was investigated. The results showed that the inhibitory effect of undecenoylphenylalanine on tyrosinase diphenolase activity was competitive reversible inhibition, the half inhibitory concentration was 3.711g/L, and the inhibition constant (K_ I) 3.651g/L.
Key words:
DOI:
10.13218/j.cnki.csdc.2016.10.009
year:
2016
Last Update：2024-01-02 23:10:35
175357-18-3 - Monoesters of N-undecylenylphenylalanine and polyhydric alcohols, method for their preparation and use of said esters as skin lightening agents
from Palm Bridge research
Application (patent) number:
CN200980133036.4
application date:
2009-09-14
Public/Announcement Number:
CN102281861A
Public/announcement date:
2011.12.14
applicant (patent):
chemical product development company SEPPIC
inventor:
S · Durant C · Tagrisso J · Gilb ,C · Stoltz ,S · caevado
National and provincial code:
FR
Abstract:
The present invention relates to compounds of formula (I) in which m is an integer of 0 or 1 and p is an integer of 0,1,2 or 3. The invention also relates to a process for the preparation of said compounds, to the use of said compounds as skin lightening agents and to Cosmetic compositions and medicaments containing said compounds.
Last Update：2023-08-16 22:05:47
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