17609-80-2

Name	4-amino-3-chlorophenol
Synonyms	lenvaint-G Brn 2802558 BRN 2802558 Einecs 241-583-3 4-AMINO-3-CHLOROPHENOL 3-chloro-4-aminophenol 4-amino-3-chlorophenol 3-Chloro-4-aminophenol 4-amino-3-chloro-pheno AMINO(4-)-3-CHLOROPHENOL Phenol, 4-amino-3-chloro- 3-13-00-01184 (Beilstein Handbook Reference)
CAS	17609-80-2
EINECS	241-583-3
InChI	InChI=1S/C6H6ClNO/c7-5-3-4(9)1-2-6(5)8/h1-3,9H,8H2

Molecular Formula	C6H6ClNO
Molar Mass	143.57
Density	1.406±0.06 g/cm3(Predicted)
Melting Point	159-160℃
Boling Point	287.3±25.0 °C(Predicted)
Flash Point	131.8°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.00074mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	9.26±0.18(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.606

RTECS	SJ5710000
Hazard Class	6.1

introduction	4-amino -3-chlorophenol is an important pharmaceutical and chemical intermediate, which is widely used in the design and synthesis of anti-tumor, cardiovascular disease, neurological disease and other drugs. It is an important intermediate for the preparation of new tyrosine kinase inhibitors, tivozani (Tivozanib) and lenvatinib (Lenvatinib).
Use	4-amino-3-chlorophenol is a phenolic derivative and can be used as an intermediate of lenvatinib (lenvatinib).

Last Update：2024-04-09 20:52:54

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