177760-52-0 - Names and Identifiers
Name | Ethyl 2-Aminooxazole-4-Carboxylate
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Synonyms | ETHYL 2-AMINO-4-OXAZOLECARBOXYLATE Ethyl 2-Aminooxazole-4-Carboxylate Ethyl 2-Amino-4-oxazolecarboxylate Ethyl 2-amino-1,3-oxazole-4-carboxylate 2-AMinooxazole-4-carboxylate ethyl ester 4-Oxazolecarboxylicacid,2-amino-,ethylester 2-Amino-4-oxazolecarboxylic Acid Ethyl Ester 2-Aminooxazole-4-carboxylic acid ethyl ester 2-AMINOOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 2-Amino-oxazole-4-carboxylic acid ethyl ester 4-Oxazolecarboxylicacid,2-amino-,ethylester(9CI) 2-AMino-1,3-Isoxazole-4-Carboxylic Acid Ethylester
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CAS | 177760-52-0
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InChI | InChI=1/C6H8N2O3/c1-2-10-5(9)4-3-11-6(7)8-4/h3H,2H2,1H3,(H2,7,8) |
InChIKey | NBABLVASYFPOEV-UHFFFAOYSA-N |
177760-52-0 - Physico-chemical Properties
Molecular Formula | C6H8N2O3
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Molar Mass | 156.14 |
Density | 1.278±0.06 g/cm3(Predicted) |
Melting Point | 124-128 |
Boling Point | 282.9±32.0 °C(Predicted) |
Flash Point | 124.918°C |
Vapor Presure | 0.003mmHg at 25°C |
Appearance | Light brown solid |
pKa | 2.82±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.523 |
MDL | MFCD06659907 |
Physical and Chemical Properties | Storage Conditions: Keep Cold |
177760-52-0 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Safety Description | 24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
HS Code | 29349990 |
Hazard Note | Harmful/Irritant/Keep Cold |
Hazard Class | IRRITANT |
177760-52-0 - Introduction
Ethyl is an organic compound with the chemical formula C6H7N3O3. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: Ethyl L for white crystalline powder solid.
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane, insoluble in water.
-Melting point: About 158-160 ° C.
Use:
- Ethyl L is mainly used as an intermediate for the synthesis of drugs, especially oxazoles and amides.
-It can also be used as a raw material for the synthesis of pesticides, such as insecticides, fungicides and herbicides.
Method:
-Generally, the synthesis of Ethyl L is completed through a four-step reaction.
1. Ethanone reacts with aminoethanol to obtain 2-aminoethanone by ketonation.
2. 2-aminoethanone reacts with formic acid and dichloromethane under alkaline conditions to generate ethyl 2-aminooxazole-4-carboxylate.
3. 2-Aminooxazole-4-carboxylic acid Ethyl ester generates Ethyl phenyl through hydrolysis reaction.
4. Finally, the final product was obtained by crystallization purification.
Safety Information:
The specific toxicity and harmfulness of-Ethyl L has not been fully determined, but it can be used as a potential organic compound and should be handled with caution.
-During use, you must follow relevant laboratory procedures and pay attention to personal protective measures, such as wearing gloves, protective glasses and respiratory protective equipment.
-If you accidentally touch or inhale the substance, wash the affected area immediately and seek medical advice.
Please note that the information provided here is for reference only. Please be cautious when using or handling the substance and operate according to specific experimental operations and safety regulations.
Last Update:2024-04-09 21:00:56