178172-26-4 - Names and Identifiers
Name | 1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate
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Synonyms | Saxagliptin Intermediate 1 Ethyl N-Boc-L-proline-4-ene ethyl N- Boc- 4,5- dehydroprolinate (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethylester (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester (S)-1-tert-Butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate 1-tert-butyl 2-ethyl (2S)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate 1-O-tert-butyl 2-O-ethyl (2S)-2,3-dihydropyrrole-1,2-dicarboxylate (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic?acid?1-(1,1-dimethylethyl)-5-ethyl?ester
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CAS | 178172-26-4
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InChI | InChI=1/C12H19NO4/c1-5-16-10(14)9-7-6-8-13(9)11(15)17-12(2,3)4/h6,8-9H,5,7H2,1-4H3/t9-/m0/s1 |
178172-26-4 - Physico-chemical Properties
Molecular Formula | C12H19NO4
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Molar Mass | 241.28 |
Density | 1.125±0.06 g/cm3(Predicted) |
Boling Point | 315.6±42.0 °C(Predicted) |
Flash Point | 144.689°C |
Vapor Presure | 0mmHg at 25°C |
pKa | -2.52±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.49 |
178172-26-4 - Introduction
1-tert-butyl 2-ethyl (2S)-2, 2, 2-dicarboxylate, also known as (S)-forsaline. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(S)-Forsaline is a white crystalline solid. Its molecular formula is C12H17NO3 and its molecular weight is 227.27g/mol. Its melting point is about 89-91°C. The compound is stable at room temperature and hardly decomposes.
Use:
Foxalin is a compound widely used in the field of medicine. It is used primarily as a local anesthetic and as an anticholinesterase agent. In anesthesiology, forsaline is commonly used in topical anesthesia and eye surgery to produce a local anesthetic effect and reduce pain. In addition, forsaline can also be used for research and treatment in other areas of medicine.
Method:
The preparation method of foxalin is complicated. A common synthetic method is by esterification between 1-tert-butoxycarbonyl-3-mercapto-2-propanol and ethyl maleate.
Safety Information:
Fossaline is considered relatively safe in pharmaceutical applications, but guidelines for proper use and storage are still to be followed. In the use of forsaline, care should be taken to prevent the eyes and inhalation. In case of accidental contact, flush with plenty of water and seek medical assistance. Forsaline should also be kept away from heat sources and flammable substances.
In General, Foxalin is a compound with local anesthetic effect and is widely used in the medical field. Its preparation is complex, and proper use and storage will ensure its safety.
Last Update:2024-04-09 20:52:54