Name | ROS 234 dioxalate |
Synonyms | ROS 234 dioxalate |
CAS | 1781941-93-2 |
Molecular Formula | C15H17N5O4 |
Molar Mass | 331.33 |
In vivo study | ROS 234, centrally injected, significantly shortens pentobarbital narcosis. |
biological activity | ROS 234 dioxalate is an effective H3 antagonist. the pKB value for H3 receptor in guinea pig ileum is 9.46, the pKi value of rat brain is 8.90, and the ED50 value of isolated rat cerebral cortex is 19.12 mg/kg (intraperitoneal injection). |
target | H 2 Receptor 8.90 (pKi, Rat cerebral cortex H 3 -receptor) |
in vivo research | ROS 234, centrally injected, significantly shortens pentobarbital narcosis. |