1784932-43-9 - Names and Identifiers
1784932-43-9 - Introduction
2,2-difluoro-2-(2-(trifluoromethyl)phenyl)ethan-1-ol is an organic compound with the chemical formula C10H9F5O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Melting point:-50 ° C
-Boiling point: 106-107 ° C
-Density: 1.358g/cm³
-Solubility: Soluble in ether, dimethylformamide and methanol
Use:
- 2,2-difluoro-2-(2-(trifluoromethyl)phenyl)ethan-1-ol is an important organic synthesis intermediate, widely used in the synthesis of pesticides, drugs and other compounds.
-It can be used in the pharmaceutical field to synthesize high-value chemicals, such as anti-cancer drugs and antiviral drugs.
Method:
- 2,2-difluoro-2-(2-(trifluoromethyl)phenyl)ethan-1-ol can be prepared through different synthetic routes. The following is one of the common methods:
1. First, methyl 2,2, 2-trifluoroacetate and 2,2-difluoroacetonitrile are reacted to produce 2,2-difluoro -2-(trifluoromethyl) acetonitrile.
2. Then, 2,2-difluoro -2-(trifluoromethyl) acetonitrile was reacted with the phenyl magnesium solution to produce an intermediate.
3. Finally, the intermediate undergoes a hydroxyl protection reaction to give 2,2-difluoro-2-(2-(trifluoromethyl)phenyl)ethan-1-ol.
Safety Information:
- 2,2-difluoro-2-(2-(trifluoromethyl)phenyl)ethan-1-ol has low toxicity, but it is still necessary to pay attention to safe operation.
-Avoid contact with strong oxidants during use or storage.
-In case of contact with eyes, skin or respiratory tract, rinse immediately with water and seek medical attention.
-Please dispose of waste properly and comply with relevant regulations.
Last Update：2024-04-09 21:01:54