179557-01-8

179557-01-8 - Names and Identifiers

Name	1-TERT-BUTOXYCARBONYL-4-(CYCLOPROPYLAMINO)PIPERIDINE
Synonyms	1-BOC-4-CYCLOPROPYLAMINO-PIPERIDINE 1-N-BOC 4-(CYCLOPROPYLAMINO) PIPERIDINE 4-(Cyclopropylamino)piperidine, N1-BOC protected 1-TERT-BUTOXYCARBONYL-4-(CYCLOPROPYLAMINO)PIPERIDINE TERT-BUTYL 4-(CYCLOPROPYLAMINO)PIPERIDINE-1-CARBOXYLATE 4-Cyclopropylamino-piperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-(cyclopropylamino)-, 1,1-dimethylethyl ester tert-Butyl 4-(cyclopropylamino)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(cyclopropylamino)piperidine
CAS	179557-01-8
EINECS	942-872-3
InChI	InChI=1/C13H24N2O2/c1-13(2,3)17-12(16)15-8-6-11(7-9-15)14-10-4-5-10/h10-11,14H,4-9H2,1-3H3

179557-01-8 - Physico-chemical Properties

Molecular Formula	C13H24N2O2
Molar Mass	240.34
Density	1.06±0.1 g/cm3(Predicted)
Boling Point	329.7±35.0 °C(Predicted)
Flash Point	153.205°C
Vapor Presure	0mmHg at 25°C
pKa	8.89±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.512

179557-01-8 - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

179557-01-8 - Introduction

1-TERT-BUTOXYCARBONYL-4-(cycloprocylamino) PIPERIDINE is an organic compound with the chemical formula C14H23N3O2.

Nature:
-Appearance: White or almost white crystal
-Molecular weight: 273.35g/mol
-Melting Point: 102-104 ° C
-Solubility: Soluble in organic solvents such as ether and dichloromethane, insoluble in water

Use:
1-TERT-BUTOXYCARBONYL-4-(cycloprocylamino) PIPERIDINE is commonly used as a condensation reagent in organic synthesis. It can react with a sulfhydryl compound in a Ketal coupling reaction to form a disulfide, or with a carboxylic acid to form an ester.

Method:
The preparation of 1-TERT-BUTOXYCARBONYL-4-(cycloprocylamino) PIPERIDINE generally employs organic synthetic methods. The specific preparation method is as follows:
1. First, 1-tert-butoxy-4-(cyclopropylamino) piperidine reacts with dimethyl sulfoxide under nitrogen protection at low temperature to obtain an intermediate product.
2. Subsequently, the intermediate product was treated with a dichloromethane/triethylamine mixed solution to give 1-TERT-BUTOXYCARBONYL-4-(CYCLOPROPYLAMINO)PIPERIDINE.

Safety Information:
1-TERT-BUTOXYCARBONYL-4-(cycloprocylamino) PIPERIDINE is less toxic to humans when properly handled. But as a chemical, still need to pay attention to the following safety matters:
-Contact: Avoid direct contact with skin, eyes, etc. If contact is not careful, rinse with plenty of water and seek medical treatment immediately.
-Inhalation: Avoid inhaling its dust. Operate in a well-ventilated place. If symptoms such as difficulty breathing occur, move to a place with fresh air as soon as possible and seek medical attention.
-Storage: Store in a cool, dry place away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15