17BETA-ETHINYLESTRADIOL - Names and Identifiers
Name | 17-epi-Ethynyl Estradiol
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Synonyms | 17-epi-Ethynylestradiol 17BETA-ETHINYLESTRADIOL 17-Ethynyl-17α-estradiol 17-epi-Ethynyl Estradiol 17-epi Ethylnyl Estradiol (IMpurity A) 17-Ethynylestra-1(10),2,4-triene-3,17α-diol 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol 19-Norpregna-1,3,5(10)-triene-20-yne-3,17α-diol (8R,9S,13S,14S,17S)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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CAS | 4717-38-8
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17BETA-ETHINYLESTRADIOL - Physico-chemical Properties
Molecular Formula | C20H24O2
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Molar Mass | 296.4 |
Density | 1.21±0.1 g/cm3(Predicted) |
Boling Point | 457.2±45.0 °C(Predicted) |
pKa | 10.24±0.60(Predicted) |
Storage Condition | -20°C |
17BETA-ETHINYLESTRADIOL - Introduction
17-epi-Ethynyl Estradiol(17-epi-Ethynyl Estradiol) is a synthetic estrogenic compound. It has activity similar to natural estrogens, but its activity is weaker.
Nature:
-chemical formula: C20H24O2
-Molecular weight: 296.41g/mol
-Appearance: white or off-white crystalline powder
-Melting point: 123-126 degrees Celsius (253-259 degrees Fahrenheit)
Use:
17-epi-Ethynyl Estradiol has many uses in medicine and research, including:
-Contraceptive: As one of the components of progestin contraceptives, it is used to control and prevent unintended pregnancy
-Treatment of chronic diseases: Used to treat conditions caused by estrogen deficiency, such as menopausal syndrome and osteoporosis
-Cancer Treatment: Used in the treatment of certain types of breast and endometrial cancer
-Reproductive health: Treatment for regulating the menstrual cycle and menstrual problems in women
Preparation Method:
17-epi-Ethynyl Estradiol can be prepared by synthetic methods. One commonly used method is the reaction of Estradiol with acetylene compounds to produce 17-epi-Ethynyl Estradiol.
Safety Information:
17-epi-Ethynyl Estradiol is relatively safe for medical use, but it is still necessary to follow the doctor's guidance and advice. It may cause some side effects, such as headache, breast tenderness, nausea, etc. For pregnant and lactating women, the use of 17-epi-Ethynyl Estradiol is not suitable. Postmenopausal women and patients with breast cancer, endometrial cancer, liver disease and other diseases should also be avoided.
Last Update:2024-04-10 22:29:15