18,19-Didehydrohirsutine
Hirsuteine
CAS: 35467-43-7
Molecular Formula: C22H26N2O3
18,19-Didehydrohirsutine - Names and Identifiers
18,19-Didehydrohirsutine - Physico-chemical Properties
| Molecular Formula | C22H26N2O3 |
| Molar Mass | 366.46 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Melting Point | 92-94°C |
| Boling Point | 533.2±50.0 °C(Predicted) |
| Solubility | Soluble in chloroform, methanol, DMSO, acid water |
| Appearance | White powder or crystal |
| pKa | 18.03±0.60(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD01731844 |
| Physical and Chemical Properties | White crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from uncaria Uncaria rhynchophylla(Miq.)Miq. ex Havil.. |
18,19-Didehydrohirsutine - Reference
| Reference Show more | 1. Guo Xiaomin, Huang Baoyuan, Zeng Chang Qing. Screening of Uncaria alkaloid extract and its monomer to reverse drug resistance activity of HepG2/ADM cells [J]. Journal of Guangdong Pharmaceutical College, 2018, 034(004):447-451. 2. [IF = 4.411] Shugen Wei et al."Molecular Identification and Targeted Quantitative Analysis of Medicinal Materials from Uncaria Species by DNA Barcoding and LC-MS/MS." Molecules. 2019 Jan;24(1):175 3. [IF = 4.759] Keyu Feng et al."Configuration of the ion exchange chromatography, and reversed-phase chromatography as off-line three-dimensional chromatography coupled with high-resolution quadrupole-Orbitrap mass spectrometry fo 4. [IF=3.935] Wenwen Huang et al."Rapid discovery of potentially vasodilative compounds from Uncaria by UHPLC/Q-Orbitrap-MS based metabolomics and correlation analysis."J Pharmaceut Biomed. 2021 Nov;206:114384 5. [IF=6.529] Lingling Xie et al."Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway."Biomed Pharmacother. 2022 Feb;146:112607 |
18,19-Didehydrohirsutine - Reference Information
| biological activity | Hirsuteine is an indole alkaloid extracted from Uncaria. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through the nicotinic receptor channel complex. |
| Use | antihypertensive. for content determination/identification/pharmacological experiments, etc |
Last Update：2024-04-09 20:52:54
Supplier List
Product Name: Mitragynine Impurity 9 Request for quotation
CAS: 35467-43-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 35467-43-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Hirsuteine Visit Supplier Webpage Request for quotationCAS: 35467-43-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Mitragynine Impurity 9 Request for quotation
CAS: 35467-43-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 35467-43-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Hirsuteine Visit Supplier Webpage Request for quotationCAS: 35467-43-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History