Name | KRN5 |
Synonyms | KRN5 1800465-47-7 8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- |
CAS | 1800465-47-7 |
Molecular Formula | C27H22FNO5 |
Molar Mass | 459.47 |
Density | 1.42±0.1 g/cm3(Predicted) |
Boling Point | 682.0±55.0 °C(Predicted) |
pKa | -1.93±0.40(Predicted) |
Storage Condition | 2-8℃ |
Use | KRN5 is a derivative of KRN2, an orally active inhibitor of T cell-activated nuclear factor (NFAT5) with an IC50 value of 750 nM. KRN5 has the potential to treat nfat5-mediated chronic arthritis. |