180305-85-5
(R)-a-Phenyl-1-pyrrolidineethanamine
CAS: 180305-85-5
Molecular Formula: C12H18N2
180305-85-5 - Names and Identifiers
180305-85-5 - Physico-chemical Properties
| Molecular Formula | C12H18N2 |
| Molar Mass | 190.28 |
180305-85-5 - Introduction
(R)-a-Phenyl-1-pyrrolidineethanamine, also known as (R)-alpha-phenyl-l-pyrroleethylamine or (R)-l-phenyl-2-pyrrolidineethylamine, is a chiral compound. Its chemical formula is C11H15N, structural formula is as follows:
H
|
H-C-N
|
CH3
The compound has the following properties:
-Appearance: Colorless or light yellow liquid.
-Solubility: Soluble in ethanol, ethers, alkanes and chlorinated hydrocarbons. Slightly soluble in water.
-Melting point: approx. -82 ° C
-Boiling point: About 213-214 ° C
-Optical rotation:[α]D20 = 4.18 ° (c = 1, CHCl3)
(R)-a-Phenyl-1-pyrrolidineethanamine catalysts and chiral means commonly used in organic synthesis. It can be used as a raw material for the synthesis of drugs, pesticides, fragrances, fungicides and dyes with chiral carbon. In addition, it can also be used for the synthesis of chiral polymers and chiral liquid crystal materials.
A common method for preparing (R)-a-Phenyl-1-pyrrolidineethanamine is through the hydroxyl ring opening reaction of (R)-N-tipfenamine and bromomethylcyclohexane.
The compound has the following safety information:
-Eye Contact: May cause irritation.
-Inhalation: May cause respiratory system irritation with taste.
-Ingestion: May cause gastrointestinal irritation, nausea and vomiting.
-Skin Contact: May cause slight irritation.
-Storage: Should be stored in a cool, dry, well-ventilated place. Keep away from heat sources, ignition sources and oxidizing agents.
Although the toxicity of the compound is low, it is necessary to pay attention to safe handling during use, including wearing protective gloves, goggles and respiratory protection, and preventing contact with skin, eyes and inhalation. When using this compound, use suitable ventilation equipment or operate in a well-ventilated environment.
H
|
H-C-N
|
CH3
The compound has the following properties:
-Appearance: Colorless or light yellow liquid.
-Solubility: Soluble in ethanol, ethers, alkanes and chlorinated hydrocarbons. Slightly soluble in water.
-Melting point: approx. -82 ° C
-Boiling point: About 213-214 ° C
-Optical rotation:[α]D20 = 4.18 ° (c = 1, CHCl3)
(R)-a-Phenyl-1-pyrrolidineethanamine catalysts and chiral means commonly used in organic synthesis. It can be used as a raw material for the synthesis of drugs, pesticides, fragrances, fungicides and dyes with chiral carbon. In addition, it can also be used for the synthesis of chiral polymers and chiral liquid crystal materials.
A common method for preparing (R)-a-Phenyl-1-pyrrolidineethanamine is through the hydroxyl ring opening reaction of (R)-N-tipfenamine and bromomethylcyclohexane.
The compound has the following safety information:
-Eye Contact: May cause irritation.
-Inhalation: May cause respiratory system irritation with taste.
-Ingestion: May cause gastrointestinal irritation, nausea and vomiting.
-Skin Contact: May cause slight irritation.
-Storage: Should be stored in a cool, dry, well-ventilated place. Keep away from heat sources, ignition sources and oxidizing agents.
Although the toxicity of the compound is low, it is necessary to pay attention to safe handling during use, including wearing protective gloves, goggles and respiratory protection, and preventing contact with skin, eyes and inhalation. When using this compound, use suitable ventilation equipment or operate in a well-ventilated environment.
Last Update：2024-04-09 20:52:54
