180465-84-3

180465-84-3 - Names and Identifiers

Name	1'-benzylspiro[indoline-3,4'-piperidine]
Synonyms	1'-benzylspiro[indoline-3,4'-piperidine] spiro[indoline-3,4'-piperidine]-1'-carboxylic acid 1'-Boc-1,2-dihydro-spiro[3H-indole-3,4'-piperidine] 1'-N-BOC-1,2-DIHYDRO-1'H-SPIRO[INDOLE-3,4'-PIPERIDINE] 1'-N-Boc-1,2-Dihydro-1'H-Spiro[Indole-3,4'-Piperidine] tert-butyl spiro[indoline-3,4'-piperidine]-1'-carboxylate tert-Butyl spiro[indoline-3,4'-piperidine]-1'-carboxylate - B6095 tert-butyl spiro[1,2-dihydroindole-3,4'-piperidine]-1'-carboxylate tert-butyl 1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate tert-Butyl 1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate 1,2-Dihydrospiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-, 1,1-dimethylethyl ester
CAS	180465-84-3
InChI	InChI=1/C17H24N2O2/c1-16(2,3)21-15(20)19-10-8-17(9-11-19)12-18-14-7-5-4-6-13(14)17/h4-7,18H,8-12H2,1-3H3

180465-84-3 - Physico-chemical Properties

Molecular Formula	C17H24N2O2
Molar Mass	288.38
Density	1.15±0.1 g/cm3(Predicted)
Melting Point	173-174℃
Boling Point	426.1±45.0 °C(Predicted)
Flash Point	211.478°C
Vapor Presure	0mmHg at 25°C
pKa	5.31±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.577

180465-84-3 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29339900
Hazard Class	IRRITANT

180465-84-3 - Introduction

1 '-indoline-3 [4'-piperidine] is an organic compound with the following properties:

1. Molecular formula: C19H24N2O2
2. Appearance: white crystalline solid
3. Melting Point: 110-112 ° C
4. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane, slightly soluble in water.
5. Structural features: it is a Spiro compound containing a ring of indoline and an adjacent piperidine ring. This structure makes it have special application value in chemical synthesis.

1 '-indoline-3 [4'-piperidine] has a number of uses:

1. Chemical synthesis: It is usually used as a reagent, intermediate or protecting group in organic synthesis. During the synthesis process, it can introduce or adjust the structure of the target molecule through deprotection group reactions and other functional group conversion reactions.
2. Drug research: Due to its special ring structure, 1 '-benzylspiro[indoline-3,4'-piperidine] can be used for drug molecular design, synthesis and optimization in drug research.
3. Other applications: It can also be applied to other fields of organic synthesis research, such as materials science and coordination chemistry.

The preparation method of 1 '-indoline-3 [benzylspiro, 4'-piperidine] can generally be carried out by the following steps:

1. Using indoline as the starting material, 3,4 '-indoline-4-formaldehyde was synthesized through a multi-step reaction.
2. Condensation reaction of 4-formaldehyde group with suitable amine compound to obtain 1 '-benzylspiro[indoline-3,4'-piperidine].

When using and handling 1 '-benzylspiro[indoline-3,4'-piperidine], you need to pay attention to some safety information:

1. Avoid inhalation and skin contact: Wear protective gloves, protective glasses and protective clothing, and if necessary, wear respiratory protective equipment.
2. Avoid contact with fire: This compound can decompose at high temperature to produce toxic gases.
3. Storage: It should be stored in a cool, dry, well-ventilated place to avoid contact with oxidants, acids and alkalis.

Reminder: When using chemicals, please be sure to abide by the laboratory safety operation specifications and operate under the guidance of experienced personnel.

Last Update：2024-04-09 21:21:28