Name | AF40431 |
Synonyms | AF40431 L-Leucine, N-[(7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-yl)methyl]- |
CAS | 181125-92-8 |
Molecular Formula | C17H21NO5 |
Molar Mass | 319.35 |
biological activity | AF40431 is the first reported sortilin small molecule ligand with IC50 of 4.4 µm, kd was 0.7 µm. AF40431 binds to the neurotensin binding site of sortilin. |
Target | IC50: 4.4 µm (sortilin) Kd: 0.7 µm (sortilin) |