185022-12-2
Aminooxy-PEG2-alcohol
CAS: 185022-12-2
Molecular Formula: C4H11NO3
185022-12-2 - Names and Identifiers
| Name | Aminooxy-PEG2-alcohol |
| Synonyms | Aminooxy-PEG2-alcohol 2-(2-(aminooxy)ethoxy)ethanol Ethanol, 2-[2-(aminooxy)ethoxy]- |
| CAS | 185022-12-2 |
185022-12-2 - Physico-chemical Properties
| Molecular Formula | C4H11NO3 |
| Molar Mass | 121.14 |
| Density | 1.116±0.06 g/cm3(Predicted) |
| Boling Point | 265.9±20.0 °C(Predicted) |
| pKa | 14.39±0.10(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
185022-12-2 - Reference Information
| bioactivity | Aminooxy-PEG2-alcohol is a non-degradable ADC linker containing 2 units of PEG, it can be used to synthesize antibody-conjugated drugs (ADCS). Aminooxy-PEG2-alcohol is also a PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. |
Last Update：2024-04-09 20:02:46
