185112-61-2 - Names and Identifiers
185112-61-2 - Physico-chemical Properties
Molecular Formula | C18H12BrN
|
Molar Mass | 322.2 |
Density | 1.39 |
Melting Point | 69-70℃ |
Boling Point | 463℃ |
Flash Point | 234℃ |
Storage Condition | Sealed in dry,Room Temperature |
185112-61-2 - Introduction
9H-Carbazole, 9-(3-bromophenyl)-is an organic compound with the following properties:
1. Appearance: 9H-Carbazole, 9-(3-bromophenyl)-white or light yellow crystalline solid.
2. Solubility: 9H-Carbazole, 9-(3-bromophenyl)-is more soluble in non-polar solvents, such as ether, chloroform and dichloromethane; It is less soluble in polar solvents, such as ethanol and water.
3. Chemical properties: The compound has the characteristics of carbazole structure, and is prone to amino protonation, electrophilic substitution and nucleophilic substitution reactions.
The main uses of 9H-Carbazole, 9-(3-bromophenyl)-include:
1. Drug research: As an intermediate in the research and development of drug molecules, it can be used to synthesize biologically active compounds.
2. Dye synthesis: Carbazole compounds have good dye properties and can be used to synthesize dyes and dyes.
In terms of preparation, the synthesis method of 9H-Carbazole, 9-(3-bromophenyl)-can adopt the following steps:
1. 3-bromoacetophenone was obtained by reacting 3-bromophenyl ethanone with bromoacetyl chloride in dichloromethane through a phenylation reaction.
2. 3-bromoacetophenone reacts with ethanolamine under alkaline conditions to generate 3-bromophenylacetamide.
3. Finally, 3-bromophenylacetamide was reacted with Cyanogen trichloride under alkaline conditions to generate 9H-Carbazole, 9-(3-bromophenyl)-.
In terms of safety information, because 9H-Carbazole, 9-(3-bromophenyl)-is an organic compound, it may cause certain harm to the human body. Appropriate personal protective equipment, such as goggles, gloves, and lab clothes, is required for the experimental operation. At the same time, care should be taken to avoid inhalation of its dust or contact with the skin. During storage and handling, care should be taken to prevent contact with oxidants and heat sources to avoid hazards caused by fire and static electricity. In order to ensure safety, it is recommended to operate in a professional laboratory and refer to the safety data sheet of the chemical for correct use and handling.
Last Update:2024-04-09 21:50:46