186185-03-5
1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylicacid3,5-dimethylesterL-Lactate
CAS: 186185-03-5
Molecular Formula: C33H42N4O6
186185-03-5 - Names and Identifiers
186185-03-5 - Physico-chemical Properties
| Molecular Formula | C33H42N4O6 |
| Molar Mass | 590.71 |
| Density | 1.188±0.06 g/cm3(Predicted) |
| Boling Point | 707.5±60.0 °C(Predicted) |
| Solubility | DMSO: >10mg/mL |
| Appearance | powder |
| Color | light yellow to yellow |
| pKa | 13.94±0.46(Predicted) |
| Storage Condition | Desiccate at +4°C |
186185-03-5 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
186185-03-5 - References
| biological activity | BMS-193885 is a potent, selective, competitive and brain-permeable Neuropeptide Y1 receptor antagonist, the Ki is 3.3 nM and The IC50 value for hY1 is 5.9 nM. The selectivity is 100 times higher than that of α1 receptor and 160 times higher than that of hY2, hY4 and hY5 receptors. |
| Target | Ki: 3.3 nM (Neuropeptide Y 1 receptor) IC50: 5.9 nM (hY 1 ) |
Last Update：2024-04-09 20:49:11
