Molecular Formula | C32H52O6 |
Molar Mass | 532.75 |
Density | 1.14 |
Melting Point | 194-196℃ |
Boling Point | 641.1±55.0 °C(Predicted) |
Specific Rotation(α) | +86 (CHCl3) |
Solubility | Chloroform, methanol |
Appearance | White crystal |
pKa | 14.12±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD30478880 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Alisma orientale Oriental Waterplantain Rhizome. |
Reference Show more | 1. Wang, Lu, et al. "Comprehensive metabolic profiling of Alismatis Rhizoma triterpenes in rats based on characteristic ions and a triterpene database." Journal of pharmaceutical analysis 11.1 (2021): 96-107.https://doi.org/10.1016/j.jpha.2020.03.010 2. [IF=4.831] Lu Lu et al."Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis."Aging-Us. 2021 Jun 15; 13(11): 15353–15365 3. [IF=2.971] Yangjie Zhou et al."Alisol A 24-acetate protects oxygen–glucose deprivation-induced brain microvascular endothelial cells against apoptosis through miR-92a-3p inhibition by targeting the B-cell lymphoma-2 gene."Pharm Biol. 2021;59(1):513-524 |
Biological activity | Alisol A 24-acetate (Alisol A 24-monoacetate) is a natural product. |
chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Alisma orientale Oriental Waterplantain Rhizome. |
use | alisol A- 24-acetate has the effects of lowering blood lipid and resisting atherosclerosis. Used for content determination/identification/pharmacological experiments and other pharmacological effects: It has obvious cholesterol-lowering effect and anti-atherosclerosis effect on experimental hypercholesterolemia rabbits. |