186982-36-5
3-(Trifluoromethoxy)benzimidamide(HCl)
CAS: 186982-36-5
Molecular Formula: C8H8ClF3N2O
186982-36-5 - Names and Identifiers
| Name | 3-(Trifluoromethoxy)benzimidamide(HCl) |
| Synonyms | 3-(Trifluoromethoxy)benzimidamide(HCl) 3-(Trifluoromethoxy)benzamidine hydrochloride 3-(trifluoroMethoxy)benziMidaMide hydrochloride |
| CAS | 186982-36-5 |
| InChI | InChI=1/C8H7F3N2O.ClH/c9-8(10,11)14-6-3-1-2-5(4-6)7(12)13;/h1-4H,(H3,12,13);1H |
186982-36-5 - Physico-chemical Properties
| Molecular Formula | C8H8ClF3N2O |
| Molar Mass | 240.61 |
| Boling Point | 262.1°C at 760 mmHg |
| Flash Point | 112.3°C |
| Vapor Presure | 0.00872mmHg at 25°C |
186982-36-5 - Introduction
3-trifluoromethoxybenzamidine (HCl), also known as 3-trifluoromethoxybenzylamine hydrochloride, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless or light yellow crystal
-Molecular formula: C8H7F3NO · HCl
-Molecular weight: 247.60g/mol
-Melting point: 100-102 ° C
-Boiling point: 342.3 ° C
-Solubility: Soluble in water, soluble in alcohol, ether and ketone and other organic solvents
Use:
-3-trifluoromethoxybenzamidine (HCl) is widely used as a pharmaceutical intermediate for the synthesis of a variety of drugs, such as antitumor drugs, antipsychotic drugs and cholinesterase inhibitors.
-It can also be used as a coordination reagent to act as a catalyst in organic synthesis reactions.
Method:
-3-Trifluoromethoxybenzamidine (HCl) can be obtained by reacting p-trifluoromethoxyanisole (3-trifluoromethoxyanisole) with benzylamine in the presence of hydrochloric acid.
Safety Information:
-3-Trifluoromethoxybenzamidine (HCl) is an irritating compound. Appropriate personal protective equipment, such as gloves and glasses, must be worn during use.
-It should be operated in a well-ventilated environment to avoid inhalation or contact with skin.
-If swallowed or contact occurs, rinse immediately with water and seek medical attention as soon as possible.
Nature:
-Appearance: colorless or light yellow crystal
-Molecular formula: C8H7F3NO · HCl
-Molecular weight: 247.60g/mol
-Melting point: 100-102 ° C
-Boiling point: 342.3 ° C
-Solubility: Soluble in water, soluble in alcohol, ether and ketone and other organic solvents
Use:
-3-trifluoromethoxybenzamidine (HCl) is widely used as a pharmaceutical intermediate for the synthesis of a variety of drugs, such as antitumor drugs, antipsychotic drugs and cholinesterase inhibitors.
-It can also be used as a coordination reagent to act as a catalyst in organic synthesis reactions.
Method:
-3-Trifluoromethoxybenzamidine (HCl) can be obtained by reacting p-trifluoromethoxyanisole (3-trifluoromethoxyanisole) with benzylamine in the presence of hydrochloric acid.
Safety Information:
-3-Trifluoromethoxybenzamidine (HCl) is an irritating compound. Appropriate personal protective equipment, such as gloves and glasses, must be worn during use.
-It should be operated in a well-ventilated environment to avoid inhalation or contact with skin.
-If swallowed or contact occurs, rinse immediately with water and seek medical attention as soon as possible.
Last Update：2024-04-09 02:00:43
