188632-07-7
FMOC-DL-CHA-OH
CAS: 188632-07-7
Molecular Formula: C24H27NO4
188632-07-7 - Names and Identifiers
188632-07-7 - Physico-chemical Properties
| Molecular Formula | C24H27NO4 |
| Molar Mass | 393.48 |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
188632-07-7 - Risk and Safety
| WGK Germany | 3 |
188632-07-7 - Introduction
FMOC-DL-CHA-OH is a chemical reagent with the following properties:
1. Appearance: A white or light yellow solid.
2. Molecular formula: C28H30N2O5.
3. Molecular weight: 474.39g/mol.
4. Melting point: about 135-140 degrees Celsius.
5. Solubility: It has good solubility and can be dissolved in organic solvents, such as dimethyl sulfinamide (DMF) and dichloromethane.
6. Use temperature: The operating temperature range of the recommend is 0-25 degrees Celsius.
FMOC-DL-CHA-OH are mainly used as protecting groups in peptide synthesis. Specific uses include:
1. Protection of amino group: Fmoc protecting group can protect the amino group in alanine during peptide synthesis to prevent non-specific reaction with other groups.
2. Deprotection: The Fmoc protecting group has good removal performance and can be removed from the peptide chain by using an alkali solution (such as sodium carbonate solution) for further chemical modification.
The preparation method of the FMOC-DL-CHA-OH is as follows:
1. Cyclohexylalanine is reacted with diimidazolyl silver oxide (DCC) in dimethylthionamide (DMF) to prepare DL-cyclohexylalanine amide.
2. The prepared DL-cyclohexylalanine amide is reacted with diimidazolyl carboxylic acid (Fmoc-OSu) in DMF to generate FMOC-DL-CHA-OH.
Safety information about FMOC-DL-CHA-OH:
1. Safety precautions: Wear appropriate personal protective equipment and avoid inhalation, contact with skin and ingestion during operation.
2. Storage conditions: it should be stored in a cool, dry and airtight container, away from strong light and heat.
3. Emergency measures: if accidentally contact with skin or eyes, should immediately rinse with plenty of water and seek medical help. If ingested or inhaled, seek medical attention immediately.
1. Appearance: A white or light yellow solid.
2. Molecular formula: C28H30N2O5.
3. Molecular weight: 474.39g/mol.
4. Melting point: about 135-140 degrees Celsius.
5. Solubility: It has good solubility and can be dissolved in organic solvents, such as dimethyl sulfinamide (DMF) and dichloromethane.
6. Use temperature: The operating temperature range of the recommend is 0-25 degrees Celsius.
FMOC-DL-CHA-OH are mainly used as protecting groups in peptide synthesis. Specific uses include:
1. Protection of amino group: Fmoc protecting group can protect the amino group in alanine during peptide synthesis to prevent non-specific reaction with other groups.
2. Deprotection: The Fmoc protecting group has good removal performance and can be removed from the peptide chain by using an alkali solution (such as sodium carbonate solution) for further chemical modification.
The preparation method of the FMOC-DL-CHA-OH is as follows:
1. Cyclohexylalanine is reacted with diimidazolyl silver oxide (DCC) in dimethylthionamide (DMF) to prepare DL-cyclohexylalanine amide.
2. The prepared DL-cyclohexylalanine amide is reacted with diimidazolyl carboxylic acid (Fmoc-OSu) in DMF to generate FMOC-DL-CHA-OH.
Safety information about FMOC-DL-CHA-OH:
1. Safety precautions: Wear appropriate personal protective equipment and avoid inhalation, contact with skin and ingestion during operation.
2. Storage conditions: it should be stored in a cool, dry and airtight container, away from strong light and heat.
3. Emergency measures: if accidentally contact with skin or eyes, should immediately rinse with plenty of water and seek medical help. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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CAS: 188632-07-7
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QQ: 3008007409
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CAS: 188632-07-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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