188781-08-0

188781-08-0 - Names and Identifiers

Name	Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate
Synonyms	2-Chloro-5-(ethoxycarbonyl)-4-methylpyrimidine ETHYL 2-CHLORO-4-METHYLPYRIMIDINE-5-CARBOXYLATE Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate 2-Chloro-4-methyl-5-pyrimidinecarboxylicacidethylester 2-Chloro-4-methyl-5-pyrimidinecarboxylic acid ethyl ester 5-Pyrimidinecarboxylic acid, 2-chloro-4-methyl-, ethyl ester 2-Chloro-5-(ethoxycarbonyl)-4-methylpyrimidine, 2-Chloro-5-(ethoxycarbonyl)-4-methyl-1,3-diazine
CAS	188781-08-0
InChI	InChI=1/C8H9ClN2O2/c1-3-13-7(12)6-4-10-8(9)11-5(6)2/h4H,3H2,1-2H3

188781-08-0 - Physico-chemical Properties

Molecular Formula	C8H9ClN2O2
Molar Mass	200.62
Density	1.265
Boling Point	302.7±22.0 °C(Predicted)
Flash Point	136.9°C
Water Solubility	Slightly soluble in water.
Vapor Presure	0.000972mmHg at 25°C
pKa	-2.56±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.524
MDL	MFCD03425963

188781-08-0 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29335990

188781-08-0 - Introduction

Ethyl, also known as trimethoprim, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Usually colorless or light yellow liquid.
-Solubility: It dissolves in many organic solvents and is basically insoluble in water.
-Melting point and boiling point: The melting point is about -25 ° C, and the boiling point is about 220-230 ° C.
-Density: about 1.2g/cm³.

Use:
- Ethyl L is often used as a pesticide intermediate, such as in the synthesis of pesticides.
-It can also be used in the field of drug synthesis as an important intermediate.

Method: The preparation of
Ethyl L is generally obtained by reacting a pyrimidine compound with Ethyl chloroacetate. The reaction is carried out under suitable reaction conditions and generally requires the use of a catalyst and a solvent.

Safety Information:
- Ethyl L may hydrolyze in a humid environment and produce harmful gases.
-It is an irritating compound that may irritate the eyes, skin and respiratory tract, so care should be taken when using it.
-During storage and use, avoid contact with strong oxidants and strong acids to prevent possible dangerous reactions.
-When handling Ethyl L, please follow the relevant safety procedures and properly dispose of waste materials.

Please note that this is only a general introduction to the compounds mentioned. In the specific use and operation, please refer to the safety technical guide and relevant professional resources, and follow the correct laboratory operation and safety specifications.

Last Update：2024-04-09 20:49:11