189321-63-9

189321-63-9 - Names and Identifiers

Name	1-Boc-4-methylpiperidine-4-carboxylic acid
Synonyms	CHEMBRDG-BB 4002933 N-BOC-4-METHYL ISONIPECOTIC ACID 4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE 1-Boc-4-methyl-4-piperidinecarboxylic Acid 1-Boc-4-methylpiperidine-4-carboxylic acid N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID 1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID 1-N-Boc-4-Methyl-Piperidine-4-Carboxylic Acid N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACID 1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid 4-METHYL-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER
CAS	189321-63-9
InChI	InChI=1/C12H21NO4/c1-11(2,3)17-10(16)13-7-5-12(4,6-8-13)9(14)15/h5-8H2,1-4H3,(H,14,15)

189321-63-9 - Physico-chemical Properties

Molecular Formula	C12H21NO4
Molar Mass	243.3
Density	1.129±0.06 g/cm3(Predicted)
Boling Point	354.3±35.0 °C(Predicted)
Flash Point	168.1°C
Vapor Presure	5.65E-06mmHg at 25°C
Appearance	Crystalline powder
pKa	4.69±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.489
MDL	MFCD02179132

189321-63-9 - Risk and Safety

UN IDs	UN2811
Hazard Class	IRRITANT

189321-63-9 - Introduction

acid, often referred to simply as Boc-PIP acid, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-molecular formula: C12H19NO4
-Molecular weight: 245.28g/mol
-Melting point: 95-97 degrees Celsius
-Solubility: Soluble in organic solvents such as methanol, ethanol and ether.

Use:
Boc-PIP acid is an important intermediate in the synthesis of compounds, mainly used in the fields of medicine and chemistry:
-In the field of medicine, it is often used as a starting material for the preparation of drugs or drug candidate compounds.
-In the field of chemistry, it can be used as a protecting group (Boc protecting group) and activator reagent in organic synthesis.

Method:
The preparation of Boc-PIP acid usually requires the following steps:
1. 4-piperidinecarboxylic acid bromide methyl ester is reacted with tert-butoxy carbene (t-BuOK) or tert-butyl carbonate in an organic solvent to obtain the precursor compound of Boc-PIP acid.
2. The precursor compound is converted into Boc-PIP acid by hydrolysis or acid treatment.

Safety Information:
- Boc-PIP acid has low toxicity, because it is a chemical, it still needs to be handled with caution.
-Avoid direct contact with skin and eyes during operation, and avoid inhalation and intake.
-Use appropriate personal protective equipment, such as lab gloves and goggles.
-Maintain a well-ventilated environment during handling and storage.
-Follow national and regional regulations and safety guidelines.

Last Update：2024-04-09 20:44:15