Name | 5-Bromo-2-Chlorobenzaldehyde |
Synonyms | 2-chloro-5-bromobenzaldehyde 5-Bromo-2-Chlorobenzaldehyde Benzaldehyde, 5-broMo-2-chloro- 5-BROMO-2-CHLOROBENZALDEHYDE fandachem |
CAS | 189628-37-3 |
InChI | InChI=1/C7H4BrClO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H |
Molecular Formula | C7H4BrClO |
Molar Mass | 219.46 |
Density | 1.698 |
Melting Point | 43-46℃ |
Boling Point | 261℃ |
Flash Point | 112℃ |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.012mmHg at 25°C |
Appearance | Solid |
Color | Off-white to pale yellow |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.623 |
use | 5-bromo-2-chlorobenzaldehyde is an important pharmaceutical and chemical raw material, which can be used to synthesize multiple drugs for treating diabetes, such as Dapagliflozin, Ertugliflozin, Empagliflozin, etc. |
Preparation method | Using 5-bromo-2-chlorobenzene methanol as raw material, it is produced by oxidation in Pyridinium Chlorochromate)/CH2Cl mixed solvent. In the patent document W02004074270, PDC (pyridinium dichromate, Pyridinium dichromate) /CH2Cl is used to oxidize 5-bromo-2-chlorobenzyl methanol, and then to obtain 5-bromo-2-chlorobenzaldehyde by oxidation. |