18996-35-5
Sodium dihydrogen citrate Anhydrous
CAS: 18996-35-5
Molecular Formula: C6H7NaO7
18996-35-5 - Names and Identifiers
| Name | Sodium dihydrogen citrate Anhydrous |
| Synonyms | monosodium citrate Natriumdihydrogencitrat Sodium dihydrogen citrate Citric acid monosodium salt Monosodium dihydrogen citrate Sodium citrate monobasic anhydrous Sodium dihydrogen citrate Anhydrous CITRICACID,MONOSODIUMSALT(ANHYDROUS) sodium 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate Citric acid monosodium salt, Sodium citrate monobasic Citric acid monosodium salt, Sodium dihydrogen citrate |
| CAS | 18996-35-5 |
| EINECS | 242-734-6 |
| InChI | InChI=1/C6H8O7.Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+1/p-3 |
18996-35-5 - Physico-chemical Properties
| Molecular Formula | C6H7NaO7 |
| Molar Mass | 214.11 |
| Melting Point | 212°C(lit.) |
| Boling Point | 309.6℃ at 760mmHg |
| Water Solubility | Soluble in water. Insoluble in ethanol. |
| Solubility | H2O: 0.25M at20°C, clear, colorless |
| Appearance | White crystalline powder |
| Color | White |
| Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.15', , 'λ: 280 nm Amax: 0.05'] |
| BRN | 3920246 |
| PH | 4.07(1 mM solution);3.87(10 mM solution);3.71(100 mM solution);3.48(1000 mM solution) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00013067 |
| Physical and Chemical Properties | Colorless crystal or white crystalline powder, odorless, salty, slightly acidic. Soluble in water, insoluble in ethanol. The pH value of 10% aqueous solution is 3.4~3.8. ADI is not limited (N0 limited,FAO/WHO,1994). |
| Use | For external contraceptive tablets as foaming agent. |
18996-35-5 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | GE7950000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29181500 |
18996-35-5 - Standard
Authoritative Data Verified Data
This product is 2-hydroxypropane-1, 2, 3-tricarboxylic acid. Calculated as anhydrous, CsH80 7 should be 99. 5% ~ 100.5%.
Last Update：2024-01-02 23:10:35
18996-35-5 - Trait
Authoritative Data Verified Data
- This product is colorless translucent crystals, white particles or white crystalline powder; Odorless, extremely sour; Slightly weathered in dry air; Acidic reaction in aqueous solution.
- This product is easily soluble in water, soluble in ethanol, and slightly soluble in ether.
melting point
The melting point of this product (General rule 0612) is 152~154°C, melting and decomposition.
Last Update：2022-01-01 11:20:37
18996-35-5 - Introduction
It is soluble in water, and its salts and solutions are prone to mold.
Last Update：2022-10-16 17:14:39
18996-35-5 - Differential diagnosis
Authoritative Data Verified Data
- This product shows the identification reaction of citrate (General rule 0301).
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 263).
Last Update：2022-01-01 11:20:38
18996-35-5 - Exam
Authoritative Data Verified Data
clarity and color of solution
take this product 2. After adding 10ml of water to dissolve, check according to law (General rule 0901 and general rule 0902, first method), the solution should be clear and colorless, it shall not be deeper in comparison with the yellow No. 2 or yellow-green No. 2 Standard Colorimetric solution (General rule 0901 method 1).
chloride
take 10.0g of this product and check it according to law (General rule 0801). Compared with the control solution made of 5 .0 m l of standard sodium chloride solution, it should not be more concentrated (0. 0005%).
sulfate
take this product l .O g, check according to law (General rule 0802), compared with the standard potassium sulfate solution 1. 5ml made of the control solution, not more concentrated (0.015%).
oxalic acid drum
take l.Og of this product, add 10ml of water to dissolve, add ammonia test solution to neutralize, add 2ml of calcium chloride test solution, place at room temperature for 30 minutes, and do not produce turbidity.
easily carbonized
take this product l.O g, put it in a colorimetric tube, add 95%(g/g) sulfuric acid 1 0 m l, heat it at 90C 1 * for 1 hour, immediately let it cool, if it develops, with the control liquid (take the gasification cobalt liquid for color comparison 0. 9ml, colorimetric potassium dichromate solution 8. 9ml with colorimetric copper sulfate solution 0 .2M l mixing) comparison, not deeper.
moisture
take this product, according to the determination method of moisture (General rule 0832 first method 1), the water content shall not exceed 0 .5%.
ignition residue
not over 0841 (general rule).
calcium salt
take l.O g of this product, add 10M l of water to dissolve, add ammonia test solution to neutralize, add several drops of ammonium oxalate test solution, and do not produce turbidity.
Heavy metals
take 4.0g of this product, Add 10ml of water to dissolve, add 1 drop of phenolphthalein indicator solution, add appropriate amount of ammonia test solution to the solution to show pink, add acetate buffer (ph3.5) 2M l and water in an appropriate amount to make 0821, inspection according to law (general principles the first law), containing heavy metals shall not exceed 5 parts per million.
arsenic salt
take 0822g of this product, add 2 3M l of water to dissolve, add hydrochloric acid 5ml, check according to law (General rule 0.0001% first law), should comply with the provisions ().
Last Update：2022-01-01 11:20:39
18996-35-5 - Content determination
Authoritative Data Verified Data
take about 1.5g of this product, weigh it accurately, add 40ml of New boiling cold water to dissolve, add 3 drops of phenolphthalein indicator solution, and use sodium hydroxide titration solution (lm o l/L) titration. Each lm l sodium hydroxide titration solution (lm o l/L) corresponds to 64. 04mg of C6 H80 7.
Last Update：2022-01-01 11:20:39
18996-35-5 - Category
Authoritative Data Verified Data
pharmaceutical excipients, p H value regulator, stabilizer and acidifier.
Last Update：2022-01-01 11:20:39
18996-35-5 - Storage
Authoritative Data Verified Data
sealed storage.
Last Update：2022-01-01 11:20:40
18996-35-5 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| identification test | solubility soluble in water; Several insoluble in ethanol. Measured according to OT-42 method. The citrate test (IT-13) was positive. The potassium test (IT-27) was positive. The Ph value of the 10% sample liquid was 3.4~3.8 and determined by conventional method. |
| content analysis | is the same as the method in "mono-potassium citrate (05218). 0.1mol/L sodium hydroxide is equivalent to 10.706mg of monosodium citrate (C6H7NaO7) per ml0. |
| toxicity | ADI is not restricted (FAO/WHO,2001);GRAS(FDA,§ 182.1751,2000). |
| use limit | FAO/WHO(1984,g/kg): broth, soup, margarine, cold drink, edible caseinate, ice cream, cheese, condensed milk, all according to GMP; Processing cheese 40 (calculated as anhydrous); Low-power concentrated milk, sweet condensed milk, thin cream, 2, in combination with other stabilizers 3 (in terms of anhydrous); Milk powder, cream powder 5 (in terms of anhydrous); Jam, jelly, orange peel jelly, keep the Ph value at 2.8~3.5.GB 2760-2001: All kinds of food, GMP. |
| use | as Ph regulator, which can be used in all kinds of food according to the regulations of our country and can be used in an appropriate amount according to the production requirements. For external contraceptive tablets as foaming agent. |
| production method | first, sodium bicarbonate is stirred and dissolved in hot water, then at 85~90 "C, a calculated amount of citric acid is added for neutralization. Decolorize again and filter while hot. The filtrate is concentrated under reduced pressure, cooled and crystallized, centrifuged, washed and dried to obtain monosodium citric acid. C6H8O7 NaHCO3→C6H7NaO7 CO2↑ H2O |
Last Update：2024-05-08 12:17:23
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Product Name: Sodium citrate monobasic Visit Supplier Webpage Request for quotationCAS: 18996-35-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Sodium citrate monobasic Visit Supplier Webpage Request for quotationCAS: 18996-35-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Sodium citrate monobasic Visit Supplier Webpage Request for quotationCAS: 18996-35-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Sodium citrate monobasic Visit Supplier Webpage Request for quotation
CAS: 18996-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 18996-35-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
18996-35-5
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