191664-14-9
(2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid
CAS: 191664-14-9
Molecular Formula: C11H21NO4
191664-14-9 - Names and Identifiers
191664-14-9 - Physico-chemical Properties
| Molecular Formula | C11H21NO4 |
| Molar Mass | 231.29 |
| Density | 1.061±0.06 g/cm3(Predicted) |
| Boling Point | 360.4±25.0 °C(Predicted) |
| pKa | 4.48±0.11(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD07372880 |
191664-14-9 - Introduction
(2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylaminoic acid(Boc-(R)-2-(aminomethyl)-3-methylaminoic acid) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: white crystalline powder.
2. molecular formula: C11H21NO4.
3. Molecular weight: 235.29g/mol.
4. Melting point: about 94 ℃.
5. Stable at room temperature.
Use:
1. (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutylanoic acid is usually used as a protecting group in organic synthesis to protect specific functional groups from reactions.
2. It can also be used as an important intermediate in drug synthesis and used to synthesize biologically active compounds.
Preparation Method:
1. The synthesis of (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid is usually carried out by the following steps:
a. Reaction of (R)-2-chloro-3-methylbutyric acid with ammoformaldehyde to produce (R)-2-(aminomethyl)-3-methylbutyraldehyde.
B. The resulting aldehyde is reacted with tert-butyl formaldehyde and an acid catalyst to produce (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid.
Safety Information:
1. (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutylanoic acid has low toxicity and irritation to human body.
2. use should take appropriate personal protective measures, such as wearing gloves and protective glasses.
3. During operation and storage, avoid contact with oxidants.
Please note that when using any chemical substance, you should follow the correct operation and safety procedures, and refer to the relevant safety data sheet (SDS) and technical information.
Nature:
1. Appearance: white crystalline powder.
2. molecular formula: C11H21NO4.
3. Molecular weight: 235.29g/mol.
4. Melting point: about 94 ℃.
5. Stable at room temperature.
Use:
1. (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutylanoic acid is usually used as a protecting group in organic synthesis to protect specific functional groups from reactions.
2. It can also be used as an important intermediate in drug synthesis and used to synthesize biologically active compounds.
Preparation Method:
1. The synthesis of (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid is usually carried out by the following steps:
a. Reaction of (R)-2-chloro-3-methylbutyric acid with ammoformaldehyde to produce (R)-2-(aminomethyl)-3-methylbutyraldehyde.
B. The resulting aldehyde is reacted with tert-butyl formaldehyde and an acid catalyst to produce (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutanoic acid.
Safety Information:
1. (2R)-2-{[(tert-Butoxycarbonyl)amino]-methyl}-3-methylbutylanoic acid has low toxicity and irritation to human body.
2. use should take appropriate personal protective measures, such as wearing gloves and protective glasses.
3. During operation and storage, avoid contact with oxidants.
Please note that when using any chemical substance, you should follow the correct operation and safety procedures, and refer to the relevant safety data sheet (SDS) and technical information.
Last Update：2024-04-09 15:18:08
