192704-82-8

192704-82-8 - Names and Identifiers

Name	Eplerenone EP Impurity B
Synonyms	Eplerenone Impurity B Eplerenone EP Impurity B Eplerenone Impurity 4(Eplerenone EP Impurity B) (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-
CAS	192704-82-8

192704-82-8 - Physico-chemical Properties

Molecular Formula	C24H30O6
Molar Mass	414.4914
Density	1.30±0.1 g/cm3(Predicted)
Boling Point	592.6±50.0 °C(Predicted)

192704-82-8 - References

Use

Eplerenone (I) is a new generation of selective aldosterone antagonist developed by Pfizer, for the treatment of stage 1 and 2 hypertensive patients, the effective rate and the amplitude of lowering systolic and diastolic blood pressure were similar to those of enalapril. Eplerenone also has a good hypotensive effect in patients with essential hypertension and low renin levels who have poor effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors. Eplerenone EP impurity B is an impurity that may be generated during the preparation of eplerenone.

Last Update：2024-04-09 21:54:55