193086-15-6

193086-15-6 - Names and Identifiers

Name	Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester
Synonyms	Tert-butyl n-(1-hydroxybutan-2-yl)carbamate Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester Carbamic acid, N-[1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)
CAS	193086-15-6

193086-15-6 - Physico-chemical Properties

Molecular Formula	C9H19NO3
Molar Mass	189.25

193086-15-6 - Introduction

Carbamic acid, [1-(hydroxymethyl) prodrug]-, 1,1-dimethylethyl ester is an organic compound, usually referred to by the abbreviation Boc-ABO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystal or crystalline powder
-molecular formula: C10H21NO3
-Molecular weight: 203.28g/mol
-Melting point: approximately 76-78 ° C
-Soluble: Soluble in common organic solvents such as ether, ketone, methanol and chloroform
-Stability: It is stable under regular experimental conditions, but has certain instability to strong oxidants and strong acids

Use:
- Carbamic acid, [1-(hydroxymethyl)propyl]-, 1,1-dimethylester is an important intermediate in organic synthesis and is often used to prepare drugs and bioactive compounds
-It can be used as the synthesis of some amino acid derivatives and the preparation of photosensitive substances
- Boc-ABO protecting group (Boc protecting group) can be used to protect amino and other active groups to control the reactivity and selectivity of the compound

Method:
- Carbamic acid, [1-(hydroxymethyl)propyl]-, 1, 1-dimethylethyyl ester can be prepared by reacting 2-amino-1-butanol with di-tert-butyl carbonate in the presence of a base
-The reaction is usually carried out at low temperature, and the product is purified by crystallization or column chromatography

Safety Information:
- Boc-ABO should be operated in a well-ventilated area, using gloves and goggles.
-The compound is irritating to the skin and eyes. You should rinse with plenty of water immediately after touching it and seek medical help.
-Should be stored in a dry, cool place, avoid contact with oxidants and strong acids.
-Observe local regulations and safe practices when handling or disposing of the compound.

Last Update：2024-04-09 15:17:54