4-Hydroxycinnamamide (4-Hydroxycinnamamide) is an organic compound with the chemical formula C9H9NO2. It is a white crystalline solid, soluble in organic solvents such as ethanol and dichloromethane. 4-Hydroxycinnamamide is aromatic and has a wide range of applications in pharmaceutical synthesis and organic synthesis.
In the pharmaceutical field, 4-Hydroxycinnamamide is widely used as a raw material for sunscreens and antioxidants. It can protect the skin by inhibiting the damage of ultraviolet rays to the skin and inhibiting the generation of free radicals. In addition, it also has antibacterial, anti-inflammatory and anti-tumor biological activities, so it also has a certain potential in the field of medical research.
There are two main methods for preparing 4-Hydroxycinnamamide. One is by the reaction of p-hydroxycinnamic acid and ammonia chloride under alkaline conditions to produce 4-hydroxycinnamide. Another method is by reacting p-hydroxycinnamide with carbonyl disulfide under alkaline conditions to produce 4-hydroxycinnamide.
Pay attention to safety when using and handling 4-Hydroxycinnamamide. It is a low-toxic substance, but it still requires protective measures, such as wearing protective glasses, gloves and protective clothing. Avoid direct contact with skin and eyes, and make sure to operate in a well-ventilated area. During storage and transportation, it should be kept away from fire and sealed storage, avoid exposure to direct sunlight.