Name | (2RS)-Lotaustralin |
Synonyms | (2RS)-Lotaustralin Butanenitrile, 2-(β-D-glucopyranosyloxy)-2-methyl- |
CAS | 1973415-50-7 |
Molecular Formula | C11H19NO6 |
Molar Mass | 261.27 |
Appearance | Powder |
Storage Condition | 2-8℃ |
Reference Show more | 1. [IF=3.373] Tian Tian et al."Non-targeted screening of pyranosides in Rhodiola crenulata using an all ion fragmentation-exact neutral loss strategy combined with liquid chromatography-quadrupole time-of-flight mass spectrometry."Phytochem Analysis. 2021 Nov;32(6):103 |
Overview | salidroside, rosevir, rosarin, rosavin, tyrosol, catechin, the difference of glucoside and gallic acid established a chemical classification system, in which salidroside and gallic acid are common components of Rhodiola species. The study found that Rhodiola root contained in the root of the lotus root (Lotus stralin) ingredients in the process of grinding and beverage processing can be cyanogenic glycoside hydrolase linamarase decomposition, produce toxic components hydrogen nitrile acid, it is the main cause of convergence and constipation in the clinical application of Rhodiola extract. |
determination of content | ① sample treatment of linseed oil: take 1ml of linseed oil and 2ml of 50% acetonitrile-50% aqueous solution for ultrasonic extraction for 10min (temperature is 50 ℃, ultrasonic power is 250W) and then shake for 1min, so repeated 3 times, static stratification, after the supernatant was taken through a 0.45 micron filter, the sample solution was subjected to liquid phase analysis. ② sample treatment of flaxseed powder: Take 50% mg solid sample and add 2ml of 50% acetonitrile-aqueous solution for ultrasonic extraction for 10min (temperature 50 ℃, ultrasonic power 250W), then shake for 1min, this was repeated 3 times, and then 10000rmp was centrifuged for 2.5min, and the supernatant was taken through a 0.45 micron filter, and the sample solution was subjected to liquid phase analysis. ③ treatment of flaxseed meal: milled flaxseed meal into powder, then take 50% mg sample and add 5ml of 50% acetonitrile-aqueous solution for ultrasonic extraction for 10min (temperature 50 ℃, ultrasonic power 250W). After shaking for 1min, so repeated 3 times, and then 10000rmp centrifugation for 2.5min, take the supernatant through 0.45 micron filter, the sample solution for liquid phase analysis. (3) sample determination: step (2) The liquid phase analysis of the obtained sample solution was carried out, and the liquid phase analysis conditions were as follows: the column of the AtlantisC column; The mobile phase: acetonitrile-water (85:15,V/V); The flow rate was 1mL/min, column temperature 30 degrees C, sample volume 5 L. Using a vapor luminescence detector (ELSD), gas flow rate 2L/min, drift tube temperature 85 degrees Celsius, the gain value is 2. (4) The calculation of the content of linopicrin and the content of the root: the sample spectrum obtained in step (3) is located and integrated, and the peak area is obtained. The resulting standard curve calculates the concentrations of linopicrin and bendolide in the sample, thereby obtaining the contents of linopicrin and bendolide in the corresponding linseed product. |
biological activity | Lotus stralin is a cyanoglycoside compound isolated from Manihot esculenta. |