19771-63-2

Name	R(-)-2-oxothiazolidine-4-carboxylic acid
Synonyms	Procysteine Oxothiazolidine carboxylate L-2-Thiazolidinone-4-carboxylic acid L-2-Thiazolidinone-4-carboxylic Acid R(-)-2-oxothiazolidine-4-carboxylic acid (4R)-2-Oxothiazolidine-4-carboxylic acid (4R)-2-Oxothiazolidine-4α-carboxylic acid (4R)-2-ketothiazolidine-4-carboxylic acid L-(-)-2-Oxo-4-thiazolidinecarboxylic Acid 4-Thiazolidinecarboxylicacid, 2-oxo-, (4R)- L-Thiazolidin-2-one-4-carboxylic acid, OTC, Procysteine, OTZ L-2-Thiazolidinone-4-carboxylic Acid,L-2-Oxothiazolidine-4-carboxylic Acid
CAS	19771-63-2
EINECS	200-154-8
InChI	InChI=1/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1

Molecular Formula	C4H5NO3S
Molar Mass	147.15
Density	1.582±0.06 g/cm3(Predicted)
Melting Point	174°C (dec.)(lit.)
Specific Rotation(α)	-60 º (c=1 in H2O)
Water Solubility	Soluble in water
Solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance	White to off-white powder
Color	White to Off-white
Merck	13,7019
BRN	4179169
pKa	pKa (22°): 3.32
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	-64 ° (C=1, H2O)
MDL	MFCD00066092

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
RTECS	XJ5426650

biological activity	Oxothiazolidinecarboxylic acid is an antioxidant and a prodrug of cysteine. it is inert and metabolized into cysteine in cells, thus stimulating the synthesis of glutathione.
Animal Model:	Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group).
Dosage:	0.35% (w/v).
Administration:	Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk.
Result:	Increased fiber CSAs compared to the non-supplemented, alcohol-fed group.

Last Update：2024-04-09 02:00:07

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