1979-29-9

1979-29-9 - Names and Identifiers

Name	2-(trifluoromethoxy)benzoic acid
Synonyms	RARECHEM AL BO 0449 2-(trifluoromethoxy)benzoate 2-TtrifluoroMethoxybenzoicacid O-TRIFLUOROMETHOXYBENZOIC ACID 2-(TRIFLUOROMETHOXY)BENZOIC ACID 2-(trifluoromethoxy)benzoic acid Adjacent Trifluoroxide Benzoic Acids ALPHA,ALPHA,ALPHA-TRIFLUORO-O-ANISIC ACID
CAS	1979-29-9
EINECS	630-288-9
InChI	InChI=1/C8H5F3O3/c9-8(10,11)14-6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)/p-1

1979-29-9 - Physico-chemical Properties

Molecular Formula	C8H5F3O3
Molar Mass	206.12
Density	1.447±0.06 g/cm3(Predicted)
Melting Point	78 °C
Boling Point	231.6±35.0 °C(Predicted)
Flash Point	93.9°C
Solubility	soluble in Methanol
Vapor Presure	0.0345mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
BRN	2645481
pKa	2.89±0.36(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00052325

1979-29-9 - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection S37 - Wear suitable gloves.
WGK Germany	3
HS Code	29189900
Hazard Note	Irritant

1979-29-9 - Introduction

2-(trifluoromethoxy)benzoic acid (abbreviated as TFMPA) is an organic compound. The following is a description of the nature, use, formulation and safety information of TFMPA:

Nature:
TFMPA is a colorless crystal, soluble in organic solvents such as benzene and ethanol. It has strong acidity and oxidation, and is sensitive to water.

Use:
TFMPA is widely used as an acid catalyst, an oxidant and a catalyst for esterification in organic synthesis. It can promote the progress of chemical reaction and improve the selectivity and yield of reaction.

Method:
The preparation of TFMPA is usually carried out by a multi-step reaction. One common method of preparation is by reacting trifluoromethane with chloromethylbenzene to produce 2-chloromethyl-3-(trifluoromethoxy) benzene (CF3CH2OH) and the reaction substrate. Then, the reaction substrate is reacted with an oxidizing agent to obtain TFMPA.

Safety Information:
The safe operation of TFMPA should follow the safety regulations of the laboratory. Due to its acidity and oxidation, it should avoid contact with flammable materials, organic solvents and combustible gases. Appropriate personal protective equipment such as lab gloves, goggles and lab clothes should be worn during operation. At the same time, it should be operated in a well-ventilated area to prevent the accumulation of harmful gases.

Last Update：2024-04-09 21:11:58