199175-10-5

199175-10-5 - Names and Identifiers

Name	(S)-1-Boc-3-(aminomethyl)pyrrolidine
Synonyms	(S)-1-Boc-3-AminomethylPyrrolidine (S)-1-BOC-3-AMINOMETHYLPYRROLIDINE (S)-N-BOC-3-(AMINOMETHYL)PYRROLIDINE (S)-1-Boc-3-(aminomethyl)pyrrolidine (S)-N-Boc-3-(Aminomethyl)Pyrrolidine (S)-1-N-Boc-3-(Aminomethyl)Pyrrolidine (S)-1-N-BOC-3-(AMINOMETHYL)PYRROLIDINE (S)-3-(AMINOMETHYL)-1-N-BOC-PYRROLIDINE (S)-3-(Aminomethyl)-1-N-Boc-Pyrrolidine (S)-1-tert-Butoxycarbonyl-3-(aminomethyl)pyrrolidine (S)-TERT-BUTYL-3-(AMINOMETHYL)PYRROLIDINE-1-CARBOXYLATE (S)-TERT-BUTYL-3-(Aminomethyl)Pyrrolidine-1-Carboxylate (S)-tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate tert-butyl (3S)-3-(aminomethyl)pyrrolidine-1-carboxylate 3(S)-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3(S)-Aminomethyl-Pyrrolidine-1-Carboxylic Acid TERT-BUTYL ESTER (S)-3-Aminomethyl-Pyrrolidine-1-Carboxylic Acid TERT-BUTYL ESTER (S)-3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	199175-10-5
InChI	InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-5-4-8(6-11)7-12/h8H,4-7,11H2,1-3H3/t8-/m0/s1

199175-10-5 - Physico-chemical Properties

Molecular Formula	C10H20N2O2
Molar Mass	200.28
Density	1.044±0.06 g/cm3(Predicted)
Boling Point	280.3±13.0 °C(Predicted)
Flash Point	123.3°C
Vapor Presure	0.0038mmHg at 25°C
Appearance	Liquid
Color	Colorless to yellow
pKa	10.12±0.29(Predicted)
Storage Condition	2-8°C
Sensitive	Air Sensitive
Refractive Index	1.4780

199175-10-5 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
TSCA	No

199175-10-5 - Introduction

(S)-1-Boc-3-(aminomethyl)pyrrolidine is an organic compound. It is a white solid with a special structure of aminomethylpyrrolidine. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C11H19N3O2
-Molecular weight: 233.29g/mol
-Melting point: 85-88 ° C
-Boiling point: 375 ° C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and acetonitrile

Use:
(S)-1-Boc-3-(aminomethyl) cryrolidine is widely used in organic synthesis, especially as a chiral reagent. It can be used to synthesize drugs, pesticides and other organic compounds. Its chiral structure enables it to catalyze or control the stereoselectivity of chemical reactions, leading to highly stereoselective synthesis.

Method:
The preparation of (S)-1-Boc-3-(aminomethyl)pyrrolidine is generally accomplished by transformation of an existing chiral compound. The most common method is to carry out intramolecular condensation reaction of chiral alanine and pyrrolidine, and then introduce (Boc) protecting group by substitution reaction to obtain the target product.

Safety Information:
(S)-1-Boc-3-(aminomethyl)pyrrolidine is non-toxic to humans under general operating conditions. However, as an organic compound, it is necessary to pay attention to safe operation. Wear protective gloves, glasses and laboratory clothing to avoid inhalation, swallowing or direct contact with skin during use. Good ventilation should be maintained when handling the compound and the safety data sheet should be read before Laboratory operation.

Last Update：2024-04-09 20:45:29