199593-09-4
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS: 199593-09-4
Molecular Formula: C42H52N5O9P
199593-09-4 - Names and Identifiers
| Name | N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite |
| Synonyms | 2'-OMe-Ac-C Phosphoramidite 2'-OMe-Ac-C Phosphoramidite 5'-O-DMT-2'-O-Me-rC(N-Ac)-3'-CEDPA 2'-O-Methyl-rC(N-Ac)Phosphoramidite 2'-O-Methyl-rC(N-Ac)Phosphoramidite DMT-2′O-Methyl-rC(ac) Phosphoramidite 5'-DMT-2'-OMe-rC(N-Ac) Phosphoramidite N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite |
| CAS | 199593-09-4 |
| EINECS | 2017-001-1 |
| InChIKey | WNWUMIPFLOKTEZ-UAQIPLLRSA-N |
199593-09-4 - Physico-chemical Properties
| Molecular Formula | C42H52N5O9P |
| Molar Mass | 801.86 |
| Melting Point | 102 - 104°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | powder |
| Color | white to off-white |
| pKa | 10.18±0.20(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
199593-09-4 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29349990 |
199593-09-4 - Introduction
The N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is also known as ABI coupling reagent. The following is an introduction to its properties, uses, preparation methods and safety information:
Nature:
- N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a solid powder, A common solvent is dimethyl sulfide (DMSO).
-It has high stability and activity, and can be used as a coupling reagent in the synthesis of DNA and RNA.
Use:
- ABI coupling reagents are mainly used for the synthesis of phosphodiester bonds in DNA and RNA. It can be used as index primers, probes and primer modifiers for constructing nucleic acid probes and primers, as well as for nucleic acid sequencing, genome analysis, etc.
Method:
- N-Acetyl-5 synthesis of '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite usually requires more steps. A common preparation method is to synthesize the target compound through a series of chemical reactions.
Safety Information:
- N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite needs to follow the safe operation procedures of chemical laboratories during use.
-It may be toxic and irritating to the human body, so direct contact with skin and eyes should be avoided, and good ventilation conditions should be ensured.
-During use, care should be taken to avoid inhalation of dust and solution contact, avoid ingestion, and prevent reactions with other chemicals.
-If accidental splashing or eating occurs, rinse immediately with plenty of water and seek help from a doctor.
Nature:
- N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a solid powder, A common solvent is dimethyl sulfide (DMSO).
-It has high stability and activity, and can be used as a coupling reagent in the synthesis of DNA and RNA.
Use:
- ABI coupling reagents are mainly used for the synthesis of phosphodiester bonds in DNA and RNA. It can be used as index primers, probes and primer modifiers for constructing nucleic acid probes and primers, as well as for nucleic acid sequencing, genome analysis, etc.
Method:
- N-Acetyl-5 synthesis of '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite usually requires more steps. A common preparation method is to synthesize the target compound through a series of chemical reactions.
Safety Information:
- N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3 '-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite needs to follow the safe operation procedures of chemical laboratories during use.
-It may be toxic and irritating to the human body, so direct contact with skin and eyes should be avoided, and good ventilation conditions should be ensured.
-During use, care should be taken to avoid inhalation of dust and solution contact, avoid ingestion, and prevent reactions with other chemicals.
-If accidental splashing or eating occurs, rinse immediately with plenty of water and seek help from a doctor.
Last Update：2024-04-09 20:49:11
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CAS: 199593-09-4
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Product Name: 2'-OMe-Ac-CPhosphoramidite Visit Supplier Webpage Request for quotation
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CAS: 199593-09-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite Request for quotationCAS: 199593-09-4
Tel: +86-571-88162785
Email: Lucy@verypharm.com
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