1H-Benzimidazol-4-amine
1H-Benzimidazol-4-amine
CAS: 4331-29-7
Molecular Formula: C7H7N3
1H-Benzimidazol-4-amine - Names and Identifiers
1H-Benzimidazol-4-amine - Physico-chemical Properties
| Molecular Formula | C7H7N3 |
| Molar Mass | 133.15 |
| Density | 1.367±0.06 g/cm3(Predicted) |
| Melting Point | 120-121 °C |
| Boling Point | 476.1±18.0 °C(Predicted) |
| Flash Point | 273.2°C |
| Vapor Presure | 3.15E-09mmHg at 25°C |
| pKa | 13.60±0.30(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.78 |
1H-Benzimidazol-4-amine - Risk and Safety
| Toxicity | mic-sat 100 mLg/plate MUREAV 28,273,1975 |
1H-Benzimidazol-4-amine - Introduction
1H-Benzimidazol-4-amine is an organic compound with the molecular formula C7H7N3, and its structure contains benzene ring and imidazole ring. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: 1H-Benzimidazol-4-amine is a white to light yellow crystalline solid.
-Melting point: about 215-220°C.
-Solubility: Soluble in common organic solvents such as alcohols, ethers, ketones, and poor solubility in water.
Use:
- 1H-Benzimidazol-4-amine is an important intermediate compound, which is widely used in the field of drug synthesis and dye synthesis.
-It can be used to synthesize drugs such as anti-tumor, anti-parasitic and immunomodulatory drugs.
-At the same time, 1H-Benzimidazol-4-amine can also be used in the dye industry for the synthesis of specific pigments and markers.
Preparation Method:
-A common method for preparing 1H-Benzimidazol-4-amine is obtained by the reaction of phthalamide (benzimidamide) with ammonia.
-The specific synthesis step is to first react phthalamide with ammonia in the presence of an alcohol or a base to generate an imidazole compound, and then a redox reaction to obtain 1H-Benzimidazol-4-amine.
Safety Information:
- 1H-Benzimidazol-4-amine has limited toxicity information and is a chemical. Please use appropriate protective equipment before use to avoid direct contact with skin and eyes.
-When using or handling this compound, pay attention to good ventilation conditions and avoid inhaling its dust or vapor.
-When disposing of waste, please follow local rules and regulations and properly dispose of waste to prevent pollution and harm to the environment.
Nature:
-Appearance: 1H-Benzimidazol-4-amine is a white to light yellow crystalline solid.
-Melting point: about 215-220°C.
-Solubility: Soluble in common organic solvents such as alcohols, ethers, ketones, and poor solubility in water.
Use:
- 1H-Benzimidazol-4-amine is an important intermediate compound, which is widely used in the field of drug synthesis and dye synthesis.
-It can be used to synthesize drugs such as anti-tumor, anti-parasitic and immunomodulatory drugs.
-At the same time, 1H-Benzimidazol-4-amine can also be used in the dye industry for the synthesis of specific pigments and markers.
Preparation Method:
-A common method for preparing 1H-Benzimidazol-4-amine is obtained by the reaction of phthalamide (benzimidamide) with ammonia.
-The specific synthesis step is to first react phthalamide with ammonia in the presence of an alcohol or a base to generate an imidazole compound, and then a redox reaction to obtain 1H-Benzimidazol-4-amine.
Safety Information:
- 1H-Benzimidazol-4-amine has limited toxicity information and is a chemical. Please use appropriate protective equipment before use to avoid direct contact with skin and eyes.
-When using or handling this compound, pay attention to good ventilation conditions and avoid inhaling its dust or vapor.
-When disposing of waste, please follow local rules and regulations and properly dispose of waste to prevent pollution and harm to the environment.
Last Update：2024-04-09 21:11:58
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Product Name: 1H-BENZIMIDAZOL-7-AMINE Visit Supplier Webpage Request for quotation
CAS: 4331-29-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 4331-29-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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