1H-Benzimidazole,1-(methylsulfonyl)-(9CI)
1H-Benzimidazole,1-(methylsulfonyl)-(9CI)
CAS: 43215-10-7
Molecular Formula: C8H8N2O2S
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) - Names and Identifiers
| Name | 1H-Benzimidazole,1-(methylsulfonyl)-(9CI) |
| Synonyms | 1-(methylsulfonyl)-1H-benzimidazole 1H-Benzimidazole, 1-(methylsulfonyl)- 1H-benzimidazole, 1-(methylsulfonyl)- 1H-Benzimidazole,1-(methylsulfonyl)-(9CI) |
| CAS | 43215-10-7 |
| InChI | InChI=1/C8H8N2O2S/c1-13(11,12)10-6-9-7-4-2-3-5-8(7)10/h2-6H,1H3 |
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) - Physico-chemical Properties
| Molecular Formula | C8H8N2O2S |
| Molar Mass | 196.23 |
| Density | 1.40±0.1 g/cm3(Predicted) |
| Melting Point | 198-200 °C |
| Boling Point | 380.5±25.0 °C(Predicted) |
| Flash Point | 183.9°C |
| Vapor Presure | 5.42E-06mmHg at 25°C |
| pKa | 0.51±0.10(Predicted) |
| Refractive Index | 1.651 |
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) - Introduction
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) is an organic compound whose chemical formula is C9H8N2O2S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) is a white solid with a melting point in the range of 173-176°C. It is insoluble in water and has good solubility in organic solvents such as ethanol and dichloromethane. The structure of this compound contains a benzimidazole ring and a methanesulfonyl (CH3SO2) group.
Use:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) is used as a pharmaceutical intermediate and organic synthetic reagent. It has a wide range of applications in the synthesis of organic compounds. For example, it can be used to prepare organic compounds such as pesticides, pharmaceuticals and dyes.
Preparation Method:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) preparation method mainly has two commonly used methods:
-one is obtained by the reaction of benzimidazole and methanesulfonyl chloride. The specific method is that benzimidazole is reacted with triethylamine, then methanesulfonyl chloride is added and reacted under appropriate conditions to obtain the target product.
-Another method is obtained by reacting benzimidazole with methanesulfonic acid. Specifically, benzimidazole is reacted with methanesulfonic acid in an organic solvent, followed by appropriate treatment to obtain the target product.
Safety Information:
The specific safety information of 1H-Benzimidazole,1-(methylsulfonyl)-(9CI) needs to be evaluated according to different applications and situations. Generally speaking, these organic compounds have certain toxicity and may cause harm to human body or environment. When using or handling the compound, attention should be paid to relevant safety procedures, such as wearing protective gloves, glasses and protective clothing, and avoiding contact with skin and eyes. At the same time, care should be taken to operate in a safe environment, that is, to maintain well-ventilated laboratory conditions.
It should be noted that the information provided above is for reference only. The specific nature, use, preparation method and safety information should be determined according to the specific application, and the relevant safety operation procedures should be strictly followed in the laboratory or industrial environment.
Nature:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) is a white solid with a melting point in the range of 173-176°C. It is insoluble in water and has good solubility in organic solvents such as ethanol and dichloromethane. The structure of this compound contains a benzimidazole ring and a methanesulfonyl (CH3SO2) group.
Use:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) is used as a pharmaceutical intermediate and organic synthetic reagent. It has a wide range of applications in the synthesis of organic compounds. For example, it can be used to prepare organic compounds such as pesticides, pharmaceuticals and dyes.
Preparation Method:
1H-Benzimidazole,1-(methylsulfonyl)-(9CI) preparation method mainly has two commonly used methods:
-one is obtained by the reaction of benzimidazole and methanesulfonyl chloride. The specific method is that benzimidazole is reacted with triethylamine, then methanesulfonyl chloride is added and reacted under appropriate conditions to obtain the target product.
-Another method is obtained by reacting benzimidazole with methanesulfonic acid. Specifically, benzimidazole is reacted with methanesulfonic acid in an organic solvent, followed by appropriate treatment to obtain the target product.
Safety Information:
The specific safety information of 1H-Benzimidazole,1-(methylsulfonyl)-(9CI) needs to be evaluated according to different applications and situations. Generally speaking, these organic compounds have certain toxicity and may cause harm to human body or environment. When using or handling the compound, attention should be paid to relevant safety procedures, such as wearing protective gloves, glasses and protective clothing, and avoiding contact with skin and eyes. At the same time, care should be taken to operate in a safe environment, that is, to maintain well-ventilated laboratory conditions.
It should be noted that the information provided above is for reference only. The specific nature, use, preparation method and safety information should be determined according to the specific application, and the relevant safety operation procedures should be strictly followed in the laboratory or industrial environment.
Last Update：2024-04-09 21:11:58
