1H-Benzimidazole-2-ol
1H-Benzimidazol-2-ol(9CI)
CAS: 102976-62-5
Molecular Formula: C7H6N2O
1H-Benzimidazole-2-ol - Names and Identifiers
| Name | 1H-Benzimidazol-2-ol(9CI) |
| Synonyms | CV8118UZEW 1H-Benzimidazole-2-ol 1H-Benzimidazol-2-ol(9CI) |
| CAS | 102976-62-5 |
1H-Benzimidazole-2-ol - Physico-chemical Properties
| Molecular Formula | C7H6N2O |
| Molar Mass | 134.14 |
| Density | 1.434±0.06 g/cm3(Predicted) |
| Melting Point | >300℃(lit.) |
| Boling Point | 397.4±25.0 °C(Predicted) |
| Appearance | White to bright brown powder |
| pKa | 1.40±0.50(Predicted) |
| Storage Condition | Room Temprature |
| MDL | MFCD00127894 |
1H-Benzimidazole-2-ol - Introduction
2-Hydroxybenzimidazole (2-Hydroxybenzimidazole) is an organic compound with the chemical formula C7H6N2O. Its nature is as follows:
1. Appearance: 2-hydroxybenzimidazole is a colorless crystalline solid.
2. Solubility: It is easily soluble in hot water and alcohol, slightly soluble in ether and benzene.
3. Stability: 2-hydroxybenzimidazole is stable, but it is necessary to avoid contact with strong oxidants.
Some common uses of 2-hydroxybenzimidazole include:
1. Photoluminescent agent: It can be used to prepare photoluminescent materials, such as fluorescent dyes and fluorescent markers.
2. Metal chelating agent: It can form a stable complex with metal ions and can be used in the fields of metal ion analysis and extraction.
3. Antibacterial agent: 2-hydroxybenzimidazole has certain antibacterial activity, which can be used in the research of antibacterial drugs in the field of medicine.
The common methods for preparing 2-hydroxybenzimidazole are:
1. The condensation reaction of benzimidazole and p-hydroxyphenylacetic acid: the benzimidazole and p-hydroxyphenylacetic acid are heated and condensed under alkaline conditions to generate 2-hydroxybenzimidazole.
2. Condensation reaction of benzimidazole and 2-bromoacetic acid: Benzimidazole and 2-bromoacetic acid are heated and condensed under alkaline conditions to generate 2-hydroxybenzimidazole.
There are no clear toxicity reports regarding the safety of 2-hydroxybenzimidazole. But in general should follow good laboratory practice, avoid excessive contact and inhalation, avoid ingestion. Wear protective gloves and eyes during use to avoid contact with skin and eyes. In its preparation and application process, should have good ventilation conditions. If exposed or inhaled, wash immediately or seek medical help.
1. Appearance: 2-hydroxybenzimidazole is a colorless crystalline solid.
2. Solubility: It is easily soluble in hot water and alcohol, slightly soluble in ether and benzene.
3. Stability: 2-hydroxybenzimidazole is stable, but it is necessary to avoid contact with strong oxidants.
Some common uses of 2-hydroxybenzimidazole include:
1. Photoluminescent agent: It can be used to prepare photoluminescent materials, such as fluorescent dyes and fluorescent markers.
2. Metal chelating agent: It can form a stable complex with metal ions and can be used in the fields of metal ion analysis and extraction.
3. Antibacterial agent: 2-hydroxybenzimidazole has certain antibacterial activity, which can be used in the research of antibacterial drugs in the field of medicine.
The common methods for preparing 2-hydroxybenzimidazole are:
1. The condensation reaction of benzimidazole and p-hydroxyphenylacetic acid: the benzimidazole and p-hydroxyphenylacetic acid are heated and condensed under alkaline conditions to generate 2-hydroxybenzimidazole.
2. Condensation reaction of benzimidazole and 2-bromoacetic acid: Benzimidazole and 2-bromoacetic acid are heated and condensed under alkaline conditions to generate 2-hydroxybenzimidazole.
There are no clear toxicity reports regarding the safety of 2-hydroxybenzimidazole. But in general should follow good laboratory practice, avoid excessive contact and inhalation, avoid ingestion. Wear protective gloves and eyes during use to avoid contact with skin and eyes. In its preparation and application process, should have good ventilation conditions. If exposed or inhaled, wash immediately or seek medical help.
Last Update：2024-04-09 21:54:55
