1H-Imidazole-4,5-dicarboxamide
Imidazoledicarboxamide
CAS: 83-39-6
Molecular Formula: C5H6N4O2
1H-Imidazole-4,5-dicarboxamide - Names and Identifiers
| Name | Imidazoledicarboxamide |
| Synonyms | glycamide GLYCALPYRAMIDE Imidazoledicarboxamide Glycarbylamide Standard GLYCARBYLAMIDE STANDARD 4,5-IMIDAZOLEDICARBOXAMIDE IMIDAZOLE-4,5-DICARBOXAMIDE Imidazole-4,5-dicarboxamide 1H-Imidazole-4,5-dicarboxamide 1H-imidazole-4,5-dicarboxamide |
| CAS | 83-39-6 |
| InChI | InChI=1/C5H6N4O2/c6-4(10)2-3(5(7)11)9-1-8-2/h1H,(H2,6,10)(H2,7,11)(H,8,9) |
1H-Imidazole-4,5-dicarboxamide - Physico-chemical Properties
| Molecular Formula | C5H6N4O2 |
| Molar Mass | 154.13 |
| Density | 1.566g/cm3 |
| Boling Point | 689.6°C at 760 mmHg |
| Flash Point | 370.9°C |
| Vapor Presure | 7.23E-19mmHg at 25°C |
| Appearance | neat |
| Color | White to Almost white |
| BRN | 147831 |
| Storage Condition | 0-6°C |
| Refractive Index | 1.667 |
| MDL | MFCD00047022 |
1H-Imidazole-4,5-dicarboxamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
1H-Imidazole-4,5-dicarboxamide - Introduction
Imidazoledicarboxamide(Imidazoledicarboxamide) is an organic compound with the chemical formula C5H6N4O2. It is a white crystalline powder, soluble in some polar organic solvents such as ethanol, chloroform and dichloromethane.
This compound has a wide range of applications. It can be used as a raw material for antibacterial drugs, for example, it has a certain effect on the treatment of Streptococcus pneumoniae infection. In addition, Imidazoledicarboxamide can also be used as catalysts and ligands in organic synthesis, as crosslinkers in organic synthesis reactions and as reaction auxiliaries in polymer synthesis.
The method of synthesizing Imidazoledicarboxamide can be achieved by reacting ammonia gas and foamy hydrochloric acid in dichloromethane, and then going through some steps to finally obtain the product. The specific steps can be divided into: 1) ammonia gas is introduced into dichloromethane to generate chlorocarboxamide; 2) imidazole with formyl group located on amine is obtained by heating amine and chlorocarboxamide reaction; 3) 4-cyanoimidazole and acetyl chloride are reacted again to obtain the final Imidazoledicarboxamide product.
Regarding safety information, Imidazoledicarboxamide are generally not significantly toxic to humans under normal conditions of use. However, it is still necessary to maintain reasonable safety operations, such as avoiding direct contact with skin, inhalation of dust or vapor, and maintaining good ventilation. In addition, it is recommended to wear suitable personal protective equipment such as protective gloves and goggles during use. In case of accidental exposure or inhalation, seek medical help immediately. Remind attention to storage should be placed in a dry, cool place to avoid fire.
This compound has a wide range of applications. It can be used as a raw material for antibacterial drugs, for example, it has a certain effect on the treatment of Streptococcus pneumoniae infection. In addition, Imidazoledicarboxamide can also be used as catalysts and ligands in organic synthesis, as crosslinkers in organic synthesis reactions and as reaction auxiliaries in polymer synthesis.
The method of synthesizing Imidazoledicarboxamide can be achieved by reacting ammonia gas and foamy hydrochloric acid in dichloromethane, and then going through some steps to finally obtain the product. The specific steps can be divided into: 1) ammonia gas is introduced into dichloromethane to generate chlorocarboxamide; 2) imidazole with formyl group located on amine is obtained by heating amine and chlorocarboxamide reaction; 3) 4-cyanoimidazole and acetyl chloride are reacted again to obtain the final Imidazoledicarboxamide product.
Regarding safety information, Imidazoledicarboxamide are generally not significantly toxic to humans under normal conditions of use. However, it is still necessary to maintain reasonable safety operations, such as avoiding direct contact with skin, inhalation of dust or vapor, and maintaining good ventilation. In addition, it is recommended to wear suitable personal protective equipment such as protective gloves and goggles during use. In case of accidental exposure or inhalation, seek medical help immediately. Remind attention to storage should be placed in a dry, cool place to avoid fire.
Last Update：2024-04-09 20:52:54
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Product Name: Allopurinol Impurity 15 Visit Supplier Webpage Request for quotationCAS: 83-39-6
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Product Name: Imidazole-4,5-Dicarboxamide Visit Supplier Webpage Request for quotation
CAS: 83-39-6
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CAS: 83-39-6
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