1H-Indazole-7-lboronicacid,pinacolester

1H-Indazole-7-lboronicacid,pinacolester - Names and Identifiers

Name	1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
Synonyms	indazole 7-pinacol boronate 1H-Indazole-7-boronic aci... Indazole-7-boronic acid pinacol ester 1H-Indazole-7-lboronicacid,pinacolester 1H-Indazole-7-boronic acid pinacol ester 1H-indazol-7-ylboronic acid pinacol ester 7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 1H-INDAZOLE, 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-
CAS	915411-02-8
InChI	InChI=1S/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-7-5-6-9-8-15-16-11(9)10/h5-8H,1-4H3,(H,15,16)

1H-Indazole-7-lboronicacid,pinacolester - Physico-chemical Properties

Molecular Formula	C13H17BN2O2
Molar Mass	244.1
Storage Condition	Sealed in dry,Store in freezer, under -20°C

1H-Indazole-7-lboronicacid,pinacolester - Introduction

1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is a compound whose chemical formula is C13H16BN3O3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is a colorless or pale yellow solid.
-Melting point: Its melting point is usually in the range of 110-116°C.
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.

Use:
- 1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is commonly used as an intermediate in organic synthesis. It can be used in the synthesis of other indazole derivatives, such as drugs, dyes and coordination compounds.
-It also has some applications in the medical field, such as as anti-tumor drugs, antibacterial drugs and drugs for the treatment of epilepsy.

Method:
- 1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-has various synthesis methods. One of the main preparation methods is to obtain benzyl boronic acid compound through the condensation reaction of boric acid on benzaldehyde, and then react with indazole Grignard reagent to obtain the target product.

Safety Information:
-There is limited safety information about 1H-Indazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, so use must follow strong chemical laboratory safety procedures.
-It may be irritating to the human body, so care should be taken to avoid contact with skin, eyes and respiratory tract during operation.
-Follow standard procedures and regulations for chemical waste disposal when carrying, storing and handling compounds.

Please note that this information is for informational purposes only, and further information on the properties, uses and safety of the compound should be obtained from a reliable source before actual use.

Last Update：2024-04-09 20:49:11