1H-PYRAZOLE-4-ETHANOL - Names and Identifiers
1H-PYRAZOLE-4-ETHANOL - Physico-chemical Properties
Molecular Formula | C5H8N2O
|
Molar Mass | 112.13 |
Density | 1.228±0.06 g/cm3(Predicted) |
Melting Point | 54-55 °C |
Boling Point | 140-145 °C(Press: 0.3 Torr) |
Flash Point | 139.855°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | White solid |
pKa | 14.34±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.568 |
1H-PYRAZOLE-4-ETHANOL - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
1H-PYRAZOLE-4-ETHANOL - Introduction
2-(1H-pyrazol-4-YL)-ethanol, also known as 4-hydroxy-1h-pyrazole, is a compound with the chemical formula C7H8N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-(1H-pyrazol-4-YL)-ethanol is a colorless to pale yellow liquid.
-Solubility: It is soluble in water, alcohols and chloroform, but insoluble in non-polar solvents (such as petroleum ether).
-Melting point: Its melting point is about 19-23 degrees Celsius.
-Refining degree: generally can provide high purity 2-(1H-pyrazol-4-YL)-ethanol.
Use:
-Chemical reagent: 2-(1H-pyrazol-4-YL)-ethanol can be used as a chemical reagent and plays an important role in organic synthesis reactions.
-Drug intermediate: It can also be used as an intermediate for the preparation of drugs and has potential drug development value.
Method:
2-(1H-pyrazol-4-YL)-ethanol preparation methods are more diverse, common in the following two ways:
-keto-alcohol reaction: 2-(1H-pyrazol-4-YL)-ethanol is synthesized by reacting the pyrazole ring with a ketone.
-Dehydration reaction: When 2-(1H-pyrazol-4-YL)-ethanol reacts with acid, water will be generated, thereby generating the target product.
Safety Information:
2-(1H-pyrazol-4-YL)-ethanol is relatively safe under normal use and storage conditions, and has no obvious toxicity to the human body under general operating conditions. However, as a chemical, you should still be aware of safe handling and follow relevant safe handling regulations, such as wearing personal protective equipment, ensuring good ventilation, and avoiding contact with eyes and skin. In particular, direct inhalation and ingestion should be avoided when handling and handling the compound. If splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help if necessary.
Last Update:2024-04-09 20:45:29