1H-Pyrazole-3-carboxamide - Names and Identifiers
1H-Pyrazole-3-carboxamide - Physico-chemical Properties
Molecular Formula | C4H5N3O
|
Molar Mass | 111.1 |
Density | 1.394 |
Melting Point | 159-160 °C |
Boling Point | 469.6±18.0 °C(Predicted) |
Flash Point | 237.799°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 11.76±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.612 |
1H-Pyrazole-3-carboxamide - Risk and Safety
1H-Pyrazole-3-carboxamide - Introduction
Pyrazole-3-carboxamide is an organic compound with the chemical formula C4H4N2O. The following is a description of the nature, use, manufacture and safety information of the Pyrazole-3-carboxamide:
Nature:
-Appearance: The Pyrazole-3-carboxamide is white to light yellow crystalline powder.
-Solubility: Pyrazole-3-carboxamide insoluble in water, slightly soluble in alcohol and ether.
-Melting point: The melting point of the Pyrazole-3-carboxamide is 142-144 degrees Celsius.
Use:
-Pesticide: Pyrazole-3-carboxamide can be used as a synthetic intermediate of some pesticides, with antibacterial and insecticidal effects.
-Drugs: Pyrazole-3-carboxamide can also be used to synthesize some biologically active compounds, such as anti-cancer drugs, anti-inflammatory drugs, etc.
Method:
- Pyrazole-3-carboxamide can be obtained by the reaction of pyrazole and formyl chloride. The pyrazole is first dissolved in an organic solvent and then the formyl chloride is slowly added. After the reaction is complete, the product is washed with water and crystallized.
Safety Information:
- Pyrazole-3-carboxamide are organic compounds, with a certain degree of toxicity, should comply with the laboratory safety procedures for operation.
-Avoid skin contact and inhalation when touching Pyrazole-3-carboxamide. If contact occurs, rinse immediately with plenty of water and seek medical help.
-When storing and using Pyrazole-3-carboxamide, keep away from fire and oxidants, and store them in a cool and dry place, away from direct sunlight.
Last Update:2024-04-09 15:17:56