2',3',4',5',6'-Pentafluoroacetophenone - Names and Identifiers
Name | 2',3',4',5',6'-Pentafluoroacetophenone
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Synonyms | PENTAFLUOROACETOPHENONE 1-(pentafluorophenyl)ethanone Ethanone, 1-(pentafluorophenyl)- 2,3,4,5,6-PENTAFLUOROACETOPHENONE 2,3,4,5,6-Pentafluoroacetophenone 2',3',4',5',6'-Pentafluoroacetophenone 2',3',4',5',6'-PENTAFLUOROACETOPHENONE 1-(2,3,4,5,6-Pentafluorophenyl)ethanone Acetophenone, 2',3',4',5',6'-pentafluoro-
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CAS | 652-29-9
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EINECS | 211-487-6 |
InChI | InChI=1/C8H3F5O/c1-2(14)3-4(9)6(11)8(13)7(12)5(3)10/h1H3 |
2',3',4',5',6'-Pentafluoroacetophenone - Physico-chemical Properties
Molecular Formula | C8H3F5O
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Molar Mass | 210.1 |
Density | 1.476g/mLat 25°C(lit.) |
Melting Point | 130.5 °C |
Boling Point | 130-131°C(lit.) |
Flash Point | 150°F |
Vapor Presure | 9.68mmHg at 25°C |
Specific Gravity | 1.476 |
BRN | 2053225 |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | n20/D 1.4366(lit.) |
MDL | MFCD00000296 |
2',3',4',5',6'-Pentafluoroacetophenone - Risk and Safety
Hazard Symbols | F - Flammable
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | 24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
HS Code | 29147000 |
Hazard Note | Flammable |
2',3',4',5',6'-Pentafluoroacetophenone - Introduction
2 ',3',4 ',5',6 '-Pentafluoroacetophenone, also known as 2',3 ',4',5 ',6'-Pentafluoroacetophenone, is an organic compound. The following is a description of the nature, use, preparation and safety information of 2 ',3',4 ',5',6 '-Pentafluoroacetophenone:
Nature:
-Appearance: White solid
-Molecular formula: C8H3F5O
-Molecular weight: 210.10g/mol
-Melting point: 38-41 degrees Celsius
-Boiling point: 133-135 degrees Celsius
-Solubility: Soluble in organic solvents such as methanol and ethanol
Use:
- 2 ',3',4 ',5',6 '-Pentafluoroacetophenone is often used as an important intermediate in drug synthesis. It can be used to synthesize drugs containing fluorine compounds, such as antiambivalent amines and fluoroazoles.
- 2 ',3',4 ',5',6 '-Pentafluoroacetophenone can also be used as a reagent in organic synthesis, for example, as a catalyst in the synthesis of aromatic ketones.
Preparation Method:
- 2 ',3',4 ',5',6 '-Pentafluoroacetophenone are generally prepared by fluorinated acetophenone. A specific step is to react acetophenone with potassium pentafluoride or ammonium pentafluoride to give 2 ',3',4 ',5',6 '-Pentafluoroacetophenone. The reaction conditions are generally carried out under inert gas protection.
Safety Information:
- 2 ',3',4 ',5',6 '-Pentafluoroacetophenone are organic compounds and need to pay attention to safe operation.
-During use or operation, good laboratory practices should be observed, such as wearing appropriate protective equipment (such as gloves and glasses).
- 2 ',3',4 ',5',6 '-Pentafluoroacetophenone are irritating and contact with skin and eyes may cause irritation or burns. Therefore, direct contact and inhalation should be avoided during use.
-During handling and storage, care should be taken to prevent contact with oxidants and high-temperature substances to avoid the risk of fire or explosion.
Please note that the above information is for reference only, and specific experimental operations and safety measures still need to be evaluated and taken according to the actual situation.
Last Update:2024-04-09 20:48:19